INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2456-4184 | Impact factor: 8.76 | ESTD Year: 2016
Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 8.76 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI)
The aim of this study was to optimize and formulate fast disintegrating tablets (FDTs) of Pioglitazone using different superdisintegrants by using method i.e. direct compression method. The tablets are formulated using three superdisintegrants viz., Emcosoy, crospovidone and Croscarmellose sodium in different concentrations. Post-compression parameters and in-vitro dissolution studies were carried out. Formulation PTZN6 was compare with two different marketed formulations of different brands. Compression indicated that the prepared formulation PTZN6 containing 5 % crospovidone and 4 % Emcosoy showed 99.31 ± 0.61 % drug release in 20 min whereas marketed formulation MKT1 and MKT2 showed 85.65 ± 0.50 % and 80.78 ±0.41 % drug release within 20 min which was less than formulation PTZN6
Keywords:
superdisintegrants, tablet, fast disintegration
Cite Article:
"Fast dissolving tablet of pioglitazone with superdisintegrants.", International Journal of Novel Research and Development (www.ijnrd.org), ISSN:2456-4184, Vol.8, Issue 5, page no.771-808, May-2023, Available :http://www.ijnrd.org/papers/IJNRDTH00034.pdf
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ISSN:
2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar| ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
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