INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2456-4184 | Impact factor: 8.76 | ESTD Year: 2016
Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 8.76 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI)
Abstract
Dysmenorrhea is a medical term that describes the word ‘‘menstrual pain”, women suffer from primary and secondary dysmenorrhea. Non-steroidal anti-inflammatory medicines such as hormonal drugs are used for the treatment of dysmenorrhea, and diagnostic tests are available for dysmenorrhea such as ultrasonography, laparoscopy, and magnetic resonance imaging (MRI). Non-steroidal anti-inflammatory drugs help in reducing pain and continue to be the first-line treatment recommended for menstrual discomfort. This study evaluated various excipients for their floating behavior and in-vitro profiles of floating tablets. Purpose of floating on this review by reducing contractions of the smooth muscles of the abdomen.
This review focuses on methods for the preparation of floating tablets, the following techniques were reported as direct compression, melt granulation, melt solidification, spray drying, and wet granulation. Pre-compression parameters like angle of repose, bulk density, and tapped density, also evaluation parameters such as drug content, Differential Scanning Calorimetry (DSC), tablet thickness, friability, weight variation, in-vitro buoyancy, index swelling, and drug release were reported. This review gives an idea about the polymer which are suitable and compatible with the drug for the preparation of floating tablets and the effect of polymer, gas forming agent.
A review concludes that a floating medicine delivery device is the most effective treatment for dysmenorrhea. everyday activities are delayed by menstrual symptoms associated with dysmenorrhea, such as cramping and stomach ache. The floating drug delivery system is one of the best drug administration methods that can preserve a medication for a long period of time and increase its therapeutic efficacy. The first-line treatment for menstrual pain is still non-steroidal anti-inflammatory drugs. So floating drug delivery can be a better alternative for previously existing treatments and dosage forms.
Keywords:
Keywords: Floating tablet, Dysmenorrhea, Polymer
Cite Article:
"FLOATING DRUG DELIVERY: AN EFFECTIVE TREATMENT FOR DYSMENORRHEA", International Journal of Novel Research and Development (www.ijnrd.org), ISSN:2456-4184, Vol.8, Issue 1, page no.a191-a204, January-2023, Available :http://www.ijnrd.org/papers/IJNRD2301024.pdf
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ISSN:
2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar| ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
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