Clinical outcomes of a fully resorbable biosynthetic mesh (Poly-4-hydroxybutyrate) for abdominal wall hernia repair: our experience in India
Dr. Neeraj Goyal
, Dr. Shraiya Umashankar Tiwari , Dr. Gangadharabhatla Padmini
Abdominal hernia, resorbable biosynthetic mesh, mesh infection.
Abstract :
Introduction: In past decade, poly–4-hydroxybutyrate (P4HB) a biosynthetic fully resorbable mesh which can serve as a potential alternative to biologic and traditional synthetic meshes in abdominal wall hernia repair, circumventing issues associated with both has been introduced. Present study aims to assess assessing the clinical outcomes associated with P4HB in abdominal wall hernia repair in Indian population.
Patients and methods: A total of 25 patients at our center who underwent abdominal wall hernia repair with P4HB mesh was retrospectively reviewed to assess the postoperative outcomes associated with this mesh. The primary endpoints include the rate of recurrence and the rate of surgical site occurrence.
Results: 25 patients were included (16 women, 9 men) with an average age of 49 years and average BMI of 28.9 kg/m2. High risk comorbidities included were obesity (12%), hypertension (48%), diabetes mellitus (20%), asthma (4%), hypothyroidism (20%), coronary artery disease (8%) and malignancy (4%).
Hernia types included were umbilical (40%), infraumbilical (20%), epigastric (8%), Incisional (20%), right lumbar (4%) and inguinal (8%).
Mean defect area was 24.96 cm2. Hernias were repaired by open onlay approach in 8 patients, laparoscopic intraperitoneal onlay mesh in 15 patients and laparoscopic totally extraperitoneal in the 2 inguinal hernia patients.
At an average follow up of 18 months, only one patient developed a hernia recurrence, two patients developed surgical site infection managed conservatively and one patient complained of heaviness at the site of mesh. No patient developed a seroma/ hematoma/mesh infection/enterocutaneous fistula/need for reoperation.
Conclusion: Study data demonstrates that P4HB mesh for abdominal wall hernia repair has a favorable outcome, acceptable recurrence rate and low rate of complications. This study supports P4HB mesh as an effective and safe biomaterial for abdominal wall hernia repair.
"Clinical outcomes of a fully resorbable biosynthetic mesh (Poly-4-hydroxybutyrate) for abdominal wall hernia repair: our experience in India", IJNRD - INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT (www.IJNRD.org), ISSN:2456-4184, Vol.8, Issue 3, page no.a448-a452, March-2023, Available :https://ijnrd.org/papers/IJNRD2303048.pdf
Volume 8
Issue 3,
March-2023
Pages : a448-a452
Paper Reg. ID: IJNRD_188225
Published Paper Id: IJNRD2303048
Downloads: 000118855
Research Area: Medical Science
Country: New Delhi, New Delhi, India
ISSN: 2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar | ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
Publisher: IJNRD (IJ Publication) Janvi Wave
