Solid Lipid Nanoparticles. (A Review)

Deepak Choudhary , Dr. Nitin Bharti Gupta , Avidhesh Sharma , Prince Ritik Raj , Vishal Verma

Solid Lipid , Drug incorporation, Colloidal Drug Carriers, Surfactants.

Solid lipid nanoparticles were developed in early 1990s as an alternative to other traditional colloidal carriers like liposomes, polymeric nanoparticles and emulsions as they have advantages like controlled drug release and targeted drug delivery with increased stability. This paper gives an overview about the potential advantages and also the disadvantages of solid lipid nanoparticles, the excipients and all the different methods involved in their production including the membrane contractor method. Aspects of SLN stability and the influence of various excipients (used in SLN production) on stability with other secondary steps involved in their stabilization like freeze drying, spray drying etc. Problems associated with SLN production and instrumental techniques used in production are thoroughly discussed. Special attention is given to models of drug incorporation in SLN and the release pattern of SLN. Analytical methods involved in SLN evaluations are discussed in detail and the major applications of SLNs mainly targeted drug delivery are discussed. Keywords: Colloidal drug carriers, Solid lipid nanoparticles, Solid lipid, Surfactants, Drug incorporation.

Published Paper   E-Certificate

"Solid Lipid Nanoparticles. (A Review)", IJNRD - INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT (www.IJNRD.org), ISSN:2456-4184, Vol.8, Issue 3, page no.d91-d96, March-2023, Available :https://ijnrd.org/papers/IJNRD2303314.pdf

Volume 8 Issue 3, March-2023

Pages : d91-d96

Paper Reg. ID: IJNRD_189333

Published Paper Id: IJNRD2303314

Downloads: 000118847

Research Area: Pharmacy

Country: Samba, Jammu&Kashmir, India

Published Paper PDF: https://ijnrd.org/papers/IJNRD2303314

Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2303314

ISSN: 2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar | ESTD YEAR: 2016

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Publisher: IJNRD (IJ Publication) Janvi Wave

This work is licensed under a Creative Commons Attribution 4.0 International License and The Open Definition