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INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2456-4184 | Impact factor: 8.76 | ESTD Year: 2016 Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 8.76 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI) |
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| Paper Title: | The Vesicular Transfersome: An Permeation Enhancer Carrier of Low Permeability Drug |
| Authors Name: | Mr. Vaibhavkumar Bapu Bhagwat , Mr. Kharade Rajendra Gulab , Mr. Survase Abhijeet B. , Mr. Ban Amol Ankush |
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| Author Reg. ID: |
IJNRD_189610
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| Published Paper Id: | IJNRD2303397 |
| Published In: | Volume 8 Issue 3, March-2023 |
| DOI: | |
| Abstract: | The aim of the research was to develop the Transfersomes, a novel vesicular carrier for the better activities of anti-inflammatory by reducing the gastro intestinal toxicity which associated with oral administration. Drug including Transfersomes prepared by Thin Film Hydration Techniques using surfactants is an edge activator, phospholipids and drug use in different ratios. The prepared Transfersomes were evaluated for the particle size, entrapment efficiency, zeta potential, in vitro drug release, and transmission electron microscopy. The drug and Excipients compatibility were done by using Fourier transform infrared spectroscopy [FT-IR] and found compatible with each other. The optimized batch Transfersomes were exhibit vesicle size. The optimized batch formulations of Transfersomes were incorporated in polymer and evaluated in comparison with marketed product for drug content, pH, spreadability, in vitro permeation. The deformed vesicle formed formulation exhibit better performance in combination with edge activator rather than branded formulation. Based upon the analyzed parameters such as drug release it can be concluded that transfersome formulation containing Drug provides better permeation rate in comparison to the marketed one. |
| Keywords: | Transfersomes, Deformable and Ultra Vesicles, Transdermal Route, Edge Activators, Phosphatidylcholine, Stratum Corneum. |
| Cite Article: | "The Vesicular Transfersome: An Permeation Enhancer Carrier of Low Permeability Drug", International Journal of Novel Research and Development (www.ijnrd.org), ISSN:2456-4184, Vol.8, Issue 3, page no.d753-d759, March-2023, Available :http://www.ijnrd.org/papers/IJNRD2303397.pdf |
| Downloads: | 000118752 |
| ISSN: |
2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID:IJNRD2303397 Registration ID: 189610 Published In: Volume 8 Issue 3, March-2023 DOI (Digital Object Identifier): Page No: d753-d759 Country: Dist-Pune, Maharashtra, India Research Area: Pharmacy Publisher : IJ Publication Published Paper URL : https://www.ijnrd.org/viewpaperforall?paper=IJNRD2303397 Published Paper PDF: https://www.ijnrd.org/papers/IJNRD2303397 |
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ISSN: 2456-4184
Impact Factor: 8.76 and ISSN APPROVED
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