Paper Title
A review on gastro-retentive mucoadhesive microspheres
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Registration ID: IJNRD_193864
Published ID: IJNRD2305189
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Keywords
gastroretentive drug delivery, physiology of stomach, mucoadhesive microsphere preparation, evaluation, current research outcome.
Abstract
Drugs that are easily absorbed from the gastrointestinal tract (GIT) and have a short half-life are eliminated quickly from the blood circulation and require frequent dosing. To avoid this, and increase the gastric residence time developed GRDDS. The gastroretentive drug delivery system is a novel drug delivery system to prolong gastric retention time thereby targeting the drug to the desired site i.e. to the upper gastrointestinal tract for local or systemic action improving the bioavailability of the drugs. Mucoadhesion is the process whereby synthetic and natural polymers adhere to mucosal surfaces in the body. If these materials are then incorporated into pharmaceutical formulations, drug absorption by mucosal cells may be enhanced or the drug will be released at the site for an extended period. mucoadhesive drug delivery systems generally are the family of hydrogels, such as natural gums, polyacrylates, and cellulose ethers. Microspheres, in general, have the potential to be used for targeted and controlled-release drug delivery. Mucoadhesive microspheres are an ideal targeting system with high safety profile and have been developed for oral, buccal, nasal, ocular, rectal, and vaginal for either systemic or local effects.
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How To Cite (APA)
Rajesh h j & Dr. Parthiban S (May-2023). A review on gastro-retentive mucoadhesive microspheres. INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT, 8(5), b680-b690. https://ijnrd.org/papers/IJNRD2305189.pdf
Issue
Volume 8 Issue 5, May-2023
Pages : b680-b690
Other Publication Details
Paper Reg. ID: IJNRD_193864
Published Paper Id: IJNRD2305189
Research Area: Pharmacy
Author Type: Indian Author
Country: Mandya , Karnataka, India
Published Paper PDF: https://ijnrd.org/papers/IJNRD2305189.pdf
Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2305189
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