INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2456-4184 | Impact factor: 8.76 | ESTD Year: 2016
Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 8.76 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI)
A rapid, simple, precise and accurate high performance thin layer chromatographic method has been developed and validated for the estimation of Ganciclovir in bulk and capsule dosage form. The Ganciclovir was chromatographed on silica gel 60 F254 HPTLC plate as a stationary phase. The mobile phase was ethyl acetate: methanol: gla.acetic acid in the volume ratio of 6.0:2:0:2.0 respectively. It gave a dense and compact spot of Ganciclovir with an Rf value of 0.36. The quantitation was carried out at 250 nm. The method was validated in terms of linearity, accuracy, precision and specificity. The statistical analysis proved that the developed method is accurate and reproducible with linearity in the range of 100 to 500 ng/spot. The limit of detection and limit of quantitation for Ganciclovir were 30 and 90 ng/spot respectively. The developed method can be employed for the routine analysis of Ganciclovir in the capsule dosage form.
"Novel Analytical Design of Ganciclovir", International Journal of Novel Research and Development (www.ijnrd.org), ISSN:2456-4184, Vol.8, Issue 5, page no.d385-d388, May-2023, Available :http://www.ijnrd.org/papers/IJNRD2305352.pdf
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2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar| ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
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