Review Article on Chlamydia Trachomatis

Registration ID: IJNRD_195373

Published ID: IJNRD2305442

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Ankita Bankhele, Manisha Borkhede, Bhushan Jagtap, Yash Jadhav, Dr. Rajesh Oswal

Keywords: Chlamydia; Chronic prostatitis; Infertility orchitis; Diagnosis; Clinical signs.

Chlamydia trachomatis infections affect young, sexually active persons. Risk factors include multiple partners and failure to use condoms. The incidence of infection has increased in the past 10 years. Untreated C. trachomatis infections are responsible for a large proportion of salpingitis, ectopic pregnancy, infertility and, to a lesser extent, epididymitis. This review summarizes C. trachomatis infection in the male genitourinary tract, including urethritis, epididymitis, orchitis, and its complications, and addresses the microbiology, epidemiology, screening, clinical manifestations, diagnosis, and treatment. Screening is a possible intervention to control the infection, which is often asymptomatic. The emergence of lymphogranuloma venereum proctitis in men who have sex with men, in Europe, and of a variant with a deletion in the cryptic plasmid, in Sweden, are new features of C. trachomatis infections in the last years. A diagnosis is best made by using nucleic acid amplification tests, because they perform well and do not require invasive procedures for specimen collection. Single-dose therapy has been a significant development for treatment of an uncomplicated infection of the patient and his or her sexual partner. Antigen detection, the enzyme immunoassay test and nucleic acid hybridization tests remain important challenges. Nucleic acid amplification technologies make non-invasive urine testing cost effective and easily performed in primary care. Historically the diagnosis of C. Trachoma infections has been difficult, but newer chlamydia diagnostic tests have become clinically available in the past decade.

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Ankita Bankhele, Manisha Borkhede, Bhushan Jagtap, Yash Jadhav, & Dr. Rajesh Oswal (May-2023). Review Article on Chlamydia Trachomatis. INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT, 8(5), e371-e381. https://ijnrd.org/papers/IJNRD2305442.pdf

Volume 8 Issue 5, May-2023

Pages : e371-e381

Paper Reg. ID: IJNRD_195373

Published Paper Id: IJNRD2305442

Research Area: Pharmacy

Author Type: Indian Author

Country: Pune, Maharashtra, India

Published Paper PDF: https://ijnrd.org/papers/IJNRD2305442.pdf

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Journal Name: INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT(IJNRD)

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