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INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2456-4184 | Impact factor: 8.76 | ESTD Year: 2016 Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 8.76 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI) |
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| Paper Title: | Potential Role Of Hydrogel And Its Future Applications In Bioprinting And In-Vitro Organ Development |
| Authors Name: | Eliza Chakraborty , Adesh Nautiyal , Riya Tyagi , Deepika Pal |
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IJNRD_196464
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| Published Paper Id: | IJNRD2305644 |
| Published In: | Volume 8 Issue 5, May-2023 |
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| Abstract: | Recent studies on hydrogels have shown them as promising biomaterials for numerous applications involving tissue-engineering, drug-screening, drug-delivery, and 3-D bioprinting because they show unique physicochemical properties. The ability of these structures to hold large amounts of water is because of their hydrophilic nature that provides a soft and hydrated environment like natural tissues. This makes them ideal for mimicking the extracellular matrix and supporting cell growth and proliferation. In tissue engineering, hydrogels might be used to create scaffolds that promote cell growth and facilitate tissue regeneration. Hydrogels can also be engineered in such a way that they intimate the mechanical and biochemical in-vivocharacteristics making them a versatile tool for applications in tissue engineering. Hydrogels are being used in drug screening, as they can be functionalized with different biochemicals in order to match the microenvironment of specific tissues. This allows researchers to study how drugs interact with cells and tissues in-vitro conditions, which can lead to more efficient strategies for drug development. For applications in drug delivery hydrogels are designed to release drugs in a sustainable and controlled way, improving the drug efficacy and reducing the toxicity of drugs. Designing can also be done in a way that they can target specific tissues and cells making them a promising tool for personalized medicine. Hydrogels are being used in 3-D bioprinting, where they serve as bio-inks that can be fabricated into complex structures with high precision. In comparison to conventional technologies, this is a promising technique that allows the construction of complex three-dimensional structures in a sequential manner by a computer-aided system. One major challenge in bioprinting is finding such material that is suitable for printing and also satisfies the mechanical strength requisite for tissue engineering applications. That is where hydrogels serve as the most appropriate model and have encouraging or favorable operation potential as cell-affable materials. This technique has revolutionized tissue engineering by allowing researchers to create functional tissues and organoids and spheroids. Overall, hydrogel-based tissue engineering, drug screening, drug delivery, and 3D bioprinting are exciting areas of research with great potential to significantly impact different areas of medicine and biology. |
| Keywords: | Hydrogels, Tissue Engineering, scaffolds, 3-D Bioprinting, Drug Screening, organoids, spheroids. |
| Cite Article: | "Potential Role Of Hydrogel And Its Future Applications In Bioprinting And In-Vitro Organ Development ", International Journal of Novel Research and Development (www.ijnrd.org), ISSN:2456-4184, Vol.8, Issue 5, page no.g356-g367, May-2023, Available :http://www.ijnrd.org/papers/IJNRD2305644.pdf |
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| ISSN: |
2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID:IJNRD2305644 Registration ID: 196464 Published In: Volume 8 Issue 5, May-2023 DOI (Digital Object Identifier): Page No: g356-g367 Country: Meerut, Uttar Pradesh, India Research Area: Life Sciences Publisher : IJ Publication Published Paper URL : https://www.ijnrd.org/viewpaperforall?paper=IJNRD2305644 Published Paper PDF: https://www.ijnrd.org/papers/IJNRD2305644 |
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ISSN: 2456-4184
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