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INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2456-4184 | Impact factor: 8.76 | ESTD Year: 2016 Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 8.76 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI) |
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| Paper Title: | Formulation And Evaluation Of Tablet (Paracetamol Tablet IP) |
| Authors Name: | Mali Varsha Lingappa , Mis.S.A.Ghadge , Santosh Jain |
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| Author Reg. ID: |
IJNRD_198146
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| Published Paper Id: | IJNRD2306056 |
| Published In: | Volume 8 Issue 6, June-2023 |
| DOI: | |
| Abstract: | Abstract— Oral dosage forms are the most popular way of taking medication, despite having some disadvantages compared with other methods like risk of slow absorption of the medicament, which can be overcome by administering the drug in liquid form, therefore, possibly allowing the use of a lower dosage. However, instability of many drugs in liquid dosage form limits its use. Effervescent technique can be used as alternate to develop a dosage form which can accelerate drug disintegration and dissolution, is usually applied in quick release preparations. The tablet is added into a glass of water just before administration and the drug solution or dispersion is to be drunk immediately.[1] The tablet is quickly broken apart by internal liberation of CO2 in water due to interaction between tartaric acid and citric acid with alkali metal carbonates or bicarbonates in presence of water. Due to liberation in CO2 gas, the dissolution of API in water as well as taste masking effect is enhanced Along with the development of new pharmaceutical technique, effervescent tablet are more and more extensively to adjust the behavior of drug release, such as in sustained and controlled release preparations, pulsatile drug delivery systems, and so on. In present work an attempt has been made to formulate an effervescent tablet containing immediate release of paracetamol using various acids and bases. In present work we are used different acids and bases in different concentration. The formulation of tablets was done by using wet granulation as well as dry granulation in that technique wet granulation which was found acceptable. Then formulated tablets were evaluated for hardness, friability, weight variation, and disintegration time. [1] |
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| Cite Article: | "Formulation And Evaluation Of Tablet (Paracetamol Tablet IP) ", International Journal of Novel Research and Development (www.ijnrd.org), ISSN:2456-4184, Vol.8, Issue 6, page no.a506-a513, June-2023, Available :http://www.ijnrd.org/papers/IJNRD2306056.pdf |
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| ISSN: |
2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID:IJNRD2306056 Registration ID: 198146 Published In: Volume 8 Issue 6, June-2023 DOI (Digital Object Identifier): Page No: a506-a513 Country: DHARASHIV, MAHARASHTRA , India Research Area: Pharmacy Publisher : IJ Publication Published Paper URL : https://www.ijnrd.org/viewpaperforall?paper=IJNRD2306056 Published Paper PDF: https://www.ijnrd.org/papers/IJNRD2306056 |
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ISSN: 2456-4184
Impact Factor: 8.76 and ISSN APPROVED
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