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INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2456-4184 | Impact factor: 8.76 | ESTD Year: 2016 Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 8.76 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI) |
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| Paper Title: | Review on Griseofulvin as Antifungal agnet |
| Authors Name: | Mr. Nilesh Kothare , Miss. Pawar Madhuri , Miss. Khandagale Shital , Dr. Kamble Hemant , Mr. Waghmare Santosh |
| Download E-Certificate: | Download |
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IJNRD_199837
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| Published Paper Id: | IJNRD2306406 |
| Published In: | Volume 8 Issue 6, June-2023 |
| DOI: | |
| Abstract: | In India, dermatophyte infections have recently undergone unheard-of alterations.The effectiveness of the few primary oral antifungal medicines is not compared in any clinical studies. Dermatophytosis is treated with griseofulvin, a fungistatic antifungal drug. The dermatophytes that are frequently recognised include fungal species including Trichophyton mentagrophytes, Fusarium oxysporum, Microsporumgypseum, and Epidermophyton floccosum.may improve vascular relaxation, enhance ACE2 activity, and raise capillary blood flow.Additionally, a molecular docking analysis revealed that the receptor-binding domain (RBD) of the spike protein may prevent SARS-CoV-2 entry and viral replication when used in combination with variants of griseofulvin and its major protease, RNA-dependent RNA polymerase (RdRp), and other proteins. |
| Keywords: | drug repurposing, dermatophytic fungal, gsf gene cluster, polyketide molecule, SARS-CoV-2, spindle microtubule, and griseofulvin derivatives. |
| Cite Article: | "Review on Griseofulvin as Antifungal agnet", International Journal of Novel Research and Development (www.ijnrd.org), ISSN:2456-4184, Vol.8, Issue 6, page no.e41-e50, June-2023, Available :http://www.ijnrd.org/papers/IJNRD2306406.pdf |
| Downloads: | 000118761 |
| ISSN: |
2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID:IJNRD2306406 Registration ID: 199837 Published In: Volume 8 Issue 6, June-2023 DOI (Digital Object Identifier): Page No: e41-e50 Country: Ahmadnagar (M Corp.), Maharashtra, India Research Area: Pharmacy Publisher : IJ Publication Published Paper URL : https://www.ijnrd.org/viewpaperforall?paper=IJNRD2306406 Published Paper PDF: https://www.ijnrd.org/papers/IJNRD2306406 |
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ISSN: 2456-4184
Impact Factor: 8.76 and ISSN APPROVED
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