INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2456-4184 | Impact factor: 8.76 | ESTD Year: 2016
Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 8.76 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI)
This study formulated an alternative pain-relieving foot pad by utilizing the adopted but modified Ames (2020) protocol. It used the quantitative method, especially the true experimental design. This study was conducted in the academic year 2022-2023. Before the formulation, the researchers performed the collection and washing of the materials. Next, air-drying, dehydration, and soaking Pandakaki leaves. Thereafter followed the rotary evaporation and water bathing. In the formulation of the product, it mixed Epsom Salt (48.75g), Sea Salt (9.75g), Baking Soda (4.86g), and Pandakaki leaf extracts (2mL) in a 250mL beaker using a stirring rod. Finally, after mixing the materials thoroughly, the solution was then put in a filter tea paper and sealed, and now ready to apply with sticky paper. After the formulation, the analgesic properties of treatment, i.e, formulated alternative pain-relieving foot pad using Pandakaki (tabernaemontana pandacaqui poir) leaf extracts and positive control, i.e., Diclofenac Sodium were determined using the adopted procedures from Rashid (2017). The results revealed that both the treatment and positive control displayed analgesic properties as evidenced by the reduced number of writhing, i.e., 2, 4, 2 for treatment and 10, 14, and 12 for positive control among the mice replicates 1, 2, and 3, respectively. Hence, these findings suggest that both the treatment and the positive control manifested pain-relieving properties. Hence, it is suggested that various concentrations of the extracts to compare their tolerability may be formulated, and testing the level of toxicity of the formulations in different ratios may be performed.
"FORMULATING AN ALTERNATIVE PAIN-RELIEVING FOOT PAD USING PANDAKAKI (Tabernaemontana pandacaqui poir)", International Journal of Novel Research and Development (www.ijnrd.org), ISSN:2456-4184, Vol.8, Issue 6, page no.f226-f235, June-2023, Available :http://www.ijnrd.org/papers/IJNRD2306523.pdf
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2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar| ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
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