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INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2456-4184 | Impact factor: 8.76 | ESTD Year: 2016 Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 8.76 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI) |
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| Paper Title: | FORMULATION AND EVALUATION OF GLIPIZIDE SUSTAINED RELEASE TABLETS |
| Authors Name: | Suraj M. Gholap , Nitin D. Dhonde , Shubham D. Lambe , Amol B. Chavan |
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| Author Reg. ID: |
IJNRD_200461
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| Published Paper Id: | IJNRD2306613 |
| Published In: | Volume 8 Issue 6, June-2023 |
| DOI: | |
| Abstract: | The current study's goal was to create a sustained release (SR) tablet formulation of glipizide by combining two hydrophobic polymers with two naturally occurring hydrophilic gum resins. The preparation of several batches of Glipizide sustained release tablets moist granulation with lactose and dicalcium phosphate as diluents. The produced pills were assessed based on a number of factors. The commercial Glynase XL pills were compared with the results of an in vitro drug release research. An ideal formulation (SR F3) that contains olibanum resin and lactose as a diluent was discovered to have dissolving profiles that were comparable to those of the reference product. The Korsmeyer and Peppas model provided the best explanation for the kinetics of drug release, and a non-fickian diffusion mechanism was used to release the medication from these tablets. In conclusion, an SR formulation of Glipizide might be created using lactose as a diluent and olibanum resin as a matrix forming that regulates rate. |
| Keywords: | Glipizide, Lactose, Olibanum resin, Modified release, extended release, Release Kinetics |
| Cite Article: | "FORMULATION AND EVALUATION OF GLIPIZIDE SUSTAINED RELEASE TABLETS", International Journal of Novel Research and Development (www.ijnrd.org), ISSN:2456-4184, Vol.8, Issue 6, page no.g110-g121, June-2023, Available :http://www.ijnrd.org/papers/IJNRD2306613.pdf |
| Downloads: | 000118754 |
| ISSN: |
2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID:IJNRD2306613 Registration ID: 200461 Published In: Volume 8 Issue 6, June-2023 DOI (Digital Object Identifier): Page No: g110-g121 Country: Ahmednagar, Maharashtra, India Research Area: Pharmacy Publisher : IJ Publication Published Paper URL : https://www.ijnrd.org/viewpaperforall?paper=IJNRD2306613 Published Paper PDF: https://www.ijnrd.org/papers/IJNRD2306613 |
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ISSN: 2456-4184
Impact Factor: 8.76 and ISSN APPROVED
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