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INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2456-4184 | Impact factor: 8.76 | ESTD Year: 2016 Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 8.76 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI) |
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| Paper Title: | A Single Blind Clinical Trial to Evaluate the Efficacy of Unani Formulation in Hisath Ul Marara(Cholelithiasis) |
| Authors Name: | Dr.Syeda Sameen , Dr.Syed Abdul Khadir Hussaini , Prof. Mohd Ahsan Faroqui |
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IJNRD_217486
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| Published Paper Id: | IJNRD2404251 |
| Published In: | Volume 9 Issue 4, April-2024 |
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| Abstract: | Introduction: Cholelithiasis (Hisat-e-Marara) is a crystalline concretion formed within the gall bladder by the accretion of bile components. Gallstone disease is a major health problem leading to Surgical intervention. Various biochemical and patho-physiological factors have been reported to be associated with gallstone disease such as stasis of bile, obstruction in the bile duct, infection in the bile, obesity, oestrogen level, defective function of liver and gallbladder, reduction in bile salt concentration and various precipitating factors for stone formation. In Unani literature this disease comes under the caption Hisat-e- Safravi or Hisat ul Marara which forms in biliary tract. According to unani physicianss the causes of gall stone formation are dame ghaliz. Zoaf quwate dafeya, shiddate quwate jaziba, congenital narrowing of biliary system, khilte ghaliz wa lazuj etc.Gall stones are quite prevalent in most western countries (10%-15%). It is estimated that at least 25 million persons in the United States have gall stones, less frequent in India around 4%. Women are affected more often than men in theratio of 4:1. It is observed that gall stone is more common in FATTY, FORTY, FERTILE andFEMALES i.e, 4Fs. Aim and Objectives: To assess the safety of unani compound formulation in cases of Hisath-ul-Marara. To evaluate the efficacy of unani compound formulation in the management of Hisath-ul-Marara. Methodology: The Study was conducted as a single blind clinical trial on 40 patients in speciality Outpatient Department, Post Graduate Department Of Moalijat, Govt. Nizamia Tibbi College and General Hospital, Hyderabad. 40 Patients allocated in a single group were given the test drug in form of joshanda of kulthi (7 gm) and Powder (5gm) of Khare khask, lahsun and Naushadar, twice daily up to 90 days with five follow-ups (15th,30th,45th, 60th, 75th and 90thday). The Pre and post treatment effects were assessed based on subjective and objective parameters. Results and conclusion: The Subjective parameters like Right Hypochondric pain, Nausea, Vomiting, Indigestion, Flatulence were reduced with statistical significance (P <0.0001), and the USG findings were changed with (P=0.0319). The Test drug is effective and is found safe without any adverse events during the study period. |
| Keywords: | Key Words: cholelithiasis, Hisat-e-Marara, Hisat- e-safravi, Gall stones, concretion. |
| Cite Article: | "A Single Blind Clinical Trial to Evaluate the Efficacy of Unani Formulation in Hisath Ul Marara(Cholelithiasis)", International Journal of Novel Research and Development (www.ijnrd.org), ISSN:2456-4184, Vol.9, Issue 4, page no.c199-c218, April-2024, Available :http://www.ijnrd.org/papers/IJNRD2404251.pdf |
| Downloads: | 00027 |
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2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID:IJNRD2404251 Registration ID: 217486 Published In: Volume 9 Issue 4, April-2024 DOI (Digital Object Identifier): Page No: c199-c218 Country: Hyderabad , Telangana , India Research Area: Medical Science Publisher : IJ Publication Published Paper URL : https://www.ijnrd.org/viewpaperforall?paper=IJNRD2404251 Published Paper PDF: https://www.ijnrd.org/papers/IJNRD2404251 |
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