Paper Title
PATHOPHYSIOLOGY OF DIFFERENT CARDIOVASCULAR COMPLICATIONS IN CHRONIC KIDNEY DISEASE PATIENTS.
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Registration ID: IJNRD_216729
Published ID: IJNRD2404387
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Abstract : Chronic Kidney Disease (CKD) is a global health concern with a rising prevalence, and its impact extends beyond renal dysfunction to encompass a spectrum of systemic complications. Among these, cardiovascular complications represent a significant cause of morbidity and mortality in CKD patients. This abstract provides a comprehensive overview of the intricate relationship between CKD and cardiovascular disorders.The pathophysiological mechanisms linking CKD and cardiovascular complications are multifaceted and include traditional risk factors such as hypertension, dyslipidemia, and diabetes, as well as non-traditional factors like inflammation, oxidative stress, and mineral metabolism disturbances. The uremic milieu contributes to endothelial dysfunction, vascular calcification, and a prothrombotic state, all of which contribute to the heightened cardiovascular risk in CKD. Epidemiological studies have consistently demonstrated a strong association between declining renal function and increased cardiovascular events. This review explores the clinical manifestations of cardiovascular complications in CKD patients, including ischemic heart disease, heart failure, arrhythmias, and sudden cardiac death. Moreover, it discusses the challenges in risk stratification and management strategies unique to this population.Recent advancements in research have shed light on novel biomarkers and imaging modalities that may enhance our understanding of cardiovascular risk in CKD. Additionally, emerging therapeutic interventions, ranging from pharmacological agents targeting specific pathways to lifestyle modifications and renal replacement therapies, are discussed in the context of preventing and managing cardiovascular complications in CKD. METHODS: A comprehensive review of the existing literature was conducted to evaluate the cardiovascular complications associated with CKD patients. Relevant studies, case reports, and official reports were analyzed to identify the types, mechanisms, and incidence of these complications.
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How To Cite (APA)
Lipika Julka, DR. Nitesh Motla, & DR. Deepa Muthiah (April-2024). PATHOPHYSIOLOGY OF DIFFERENT CARDIOVASCULAR COMPLICATIONS IN CHRONIC KIDNEY DISEASE PATIENTS.. INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT, 9(4), d787-d796. https://ijnrd.org/papers/IJNRD2404387.pdf
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Volume 9 Issue 4, April-2024
Pages : d787-d796
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Paper Reg. ID: IJNRD_216729
Published Paper Id: IJNRD2404387
Research Area: Health ScienceÂ
Author Type: Indian Author
Country: NEW DELHI, DELHI, India
Published Paper PDF: https://ijnrd.org/papers/IJNRD2404387.pdf
Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2404387
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