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INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2456-4184 | Impact factor: 8.76 | ESTD Year: 2016 Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 8.76 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI) |
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| Paper Title: | A Review on Use of Glidants in Formulation of Pharmaceutical Solid dosage Forms |
| Authors Name: | Mr. S. D. Paralkar , Dr. Y. S. Thorat , Dr. B. D. Tiwari , Ms. L. A. Kawade , Ms. R. P. Kinagi |
| Download E-Certificate: | Download |
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IJNRD_218414
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| Published Paper Id: | IJNRD2404416 |
| Published In: | Volume 9 Issue 4, April-2024 |
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| Abstract: | Glidants are the substances that enhance the flow characteristics of powder mixture. To get desired effect, these are added as a dry powder before the compression process. Glidants can show their effect at certain optimum concentration only. Above certain concentration glidants itself inhibit or decreases the good flow or flow properties. Glidants act by decreasing the overall surface charge present on the blend decreasing friction between particles and filling the gaps on the surface, thus further enhancing the rate of movement and flow. Glidants are additive materials that are used to improve a powder's flowability by lowering surface charge, cohesion, and interparticle friction all of which lower the angle of repose. Angle of repose is the maximum angle between the free standing surface of powder and horizontal plane. Smaller angle indicates a good flow property compared to bigger angle. Glidants also show impact on the flow properties, product quality, granulation, particle size, uniform distribution, tablet die cavity. Glidants play vital role in pharmaceutical industry for better quality of products. Various glidants used in pharmaceutical industry are Talc, Magnesium oxide, Magnesium silicate, Silicon dioxide, etc. |
| Keywords: | Glidants, Flow property, Surface charge, Cavity filling |
| Cite Article: | "A Review on Use of Glidants in Formulation of Pharmaceutical Solid dosage Forms", International Journal of Novel Research and Development (www.ijnrd.org), ISSN:2456-4184, Vol.9, Issue 4, page no.e127-e141, April-2024, Available :http://www.ijnrd.org/papers/IJNRD2404416.pdf |
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| ISSN: |
2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID:IJNRD2404416 Registration ID: 218414 Published In: Volume 9 Issue 4, April-2024 DOI (Digital Object Identifier): Page No: e127-e141 Country: Solapur, Maharashtra, India Research Area: Pharmacy Publisher : IJ Publication Published Paper URL : https://www.ijnrd.org/viewpaperforall?paper=IJNRD2404416 Published Paper PDF: https://www.ijnrd.org/papers/IJNRD2404416 |
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ISSN: 2456-4184
Impact Factor: 8.76 and ISSN APPROVED
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