INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2456-4184 | Impact factor: 8.76 | ESTD Year: 2016
Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 8.76 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI)
In organic chemistry, aldol condensation is a basic process that forms carbon-carbon bonds and is essential to the synthesis of complex compounds. Designing and synthesizing chiral compounds with particular biological or medicinal qualities requires the capacity to manage stereoselectivity, or the relative configuration of stereocenters in the aldol process. The main ideas and current developments influencing stereoselectivity in aldol condensation processes are summarized in this abstract.
The innate diastereomeric preferences during the aldol adduct's production are the source of the stereoselectivity in aldol condensation. Temperature, solvent conditions and reactant selection are a few examples of the variables that affect stereoselectivity. L-proline acts as a sustainable and beneficial substitute for standard metal-based catalysts in aldol condensation. The system that catalyzes the reaction is mild, simple to use, and frequently produces huge quantities of the desired stereoisomer. L-proline is an asset in the toolset of synthetic organic chemists, particularly for the asymmetric synthesis of complex compounds of biological and chemical effects relevance, due to its effectiveness in stereoselective aldol condensation.
Keywords:
Stereoselectivity ,aliphatic aldehydes and aliphatic ketones, aromatic aldehydes and aromatic ketones ,L-proline
Cite Article:
"A REVIEW ON STEREOSELECTIVITY IN ALDOL CONDENSATION REACTION", International Journal of Novel Research and Development (www.ijnrd.org), ISSN:2456-4184, Vol.9, Issue 4, page no.e560-e575, April-2024, Available :http://www.ijnrd.org/papers/IJNRD2404460.pdf
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ISSN:
2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar| ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
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