Paper Title
Safety Study of a Unani Pharmacopeial compound beneficent in Urticaria (Shara)
Article Identifiers
Registration ID: IJNRD_227137
Published ID: IJNRD2408361
: https://doi.org/10.56975/ijnrd.v9i8.227137
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Keywords
Safety study, Nuqu-e-Unnab, Urticaria, microbial load, heavy metal.
Abstract
Introduction Safety is a vital component in the provision of herbal medicines and herbal products for health care, and an essential component of quality control. The quality of herbal medications has a great impact on their efficacy and safety. So, it is necessary to identify the risks associated with their use. One nuskha (prescription) was taken from Unani Pharmacopoeia consisting of single drugs Zizyphus sativa (Unnab), Prunus domestica (Aloo Bukhara), Coriandrum sativum (Kishneez Khushk), Fumaria officinalis (Shahtra) and was subjected to safety study as per the guidelines of WHO. Methods All the ingredients of the test formulation were coarsely powdered separately in an electric grinder and then mixed. The powder was then investigated for Microbial load determination, Heavy metal determination, Aflatoxins estimation, Pesticidal residue estimation and Test for specific pathogens. Result The result demonstrated that heavy metals i.e., Arsenic, Mercury, Cadmium, and lead were found present within permissible limit. Total bacterial count and total yeast and mould count were many folds lower than the permissible limit i.e. 1220 and 120 cfu/gm respectively, the specific pathogens like E. coli, Salmonella, S. aureus and P aeruginosa were found to be absent whereas Aflatotoxins B1, G1, B2, G2 as well as Pesticide residue were found absent in the test drug. Conclusion All the four examined parameters in the study are thought to be significant in determining the safety and toxicity of drugs. Since they were either present within permissible limit or were completely absent. Therefore, the test drug is considered to be safe and can safely be used for pharmacological and clinical purposes.
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How To Cite (APA)
Uzma Khatoon, Abdur Rauf, & Bilal Tafseer (August-2024). Safety Study of a Unani Pharmacopeial compound beneficent in Urticaria (Shara). INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT, 9(8), d536-d542. https://doi.org/10.56975/ijnrd.v9i8.227137
Issue
Volume 9 Issue 8, August-2024
Pages : d536-d542
Other Publication Details
Paper Reg. ID: IJNRD_227137
Published Paper Id: IJNRD2408361
Research Area: Health ScienceÂ
Author Type: Indian Author
Country: Aligarh, Uttar Pradesh, India
Published Paper PDF: https://ijnrd.org/papers/IJNRD2408361.pdf
Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2408361
Crossref DOI: https://doi.org/10.56975/ijnrd.v9i8.227137
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