A Review on Sustained Release Matrix Tablet

Shounak R. Mande

Sustained release, Polymer, Matrix tablet.

The main methods used to produce sustained release matrix tablets are wet granulation, direct compression, and the dispersion of solid particles within solid particles inside a porous matrix made of various polymers, such as polymethyl methacrylate (PMMA), polyglycolic acid, and HPMC. The matrix governs the release rate of medication. Let Go Retardants such as HPMC are essential components of the formulation because they facilitate continuous release. To create a tablet where the medicine is embedded in a matrix core of the retardant, a combination of drug, retardant material, and additives is directly compressed; alternatively, granulation can be done before compression. It is possible for the matrices to be mineral, hydrophilic, hydrophobic, or biodegradable. The rate of medication release can be examined using in vitro dissolution experiments. Drugs like ambroxol HCl and nateglinide have been developed as sustained release matrix tablets. Thus, prolonged release matrix tablets can offer better patient compliance by reduction in total dose and dosage schedule, which can be of significant help to address for long term illness.

Published Paper   E-Certificate

"A Review on Sustained Release Matrix Tablet", IJNRD - INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT (www.IJNRD.org), ISSN:2456-4184, Vol.9, Issue 10, page no.b44-b61, October-2024, Available :https://ijnrd.org/papers/IJNRD2410108.pdf

Volume 9 Issue 10, October-2024

Pages : b44-b61

Paper Reg. ID: IJNRD_301111

Published Paper Id: IJNRD2410108

Downloads: 00041

Research Area: Pharmacy All

Country: Nashik, Maharashtra, India

Published Paper PDF: https://ijnrd.org/papers/IJNRD2410108

Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2410108

ISSN: 2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar | ESTD YEAR: 2016

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

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