EFFICACY OF CAFFEINE ADMINISTRATION IN PRETERM VERY LOW BIRTH WEIGHT (VLBW) INFANTS OF SOUTH INDIA, A PROSPECTIVE OBSERVATIONAL STUDY.
Dr. SADIA RAOOF
, Dr. NEHA FATIMA
Keywords: Caffeine, Preterm neonates, Gestation, Apnea of prematurity, Retinopathy of prematurity, Bronchopulmonary dysplasia, Patent ductus arteriosus.
ABSTRACT
Background: Caffeine is used to prevent episodes of apnea in preterm neonates. It increases the rate of breathing in preterm neonates improving their breathing cycle. Study have been conducted to improve the apneic episodes in neonates using caffeine and are found to be effective in improving the condition with improvement in secondary outcomes which include reduction in extubation, retinopathy of prematurity, bronchopulmonary dysplasia, but no significant change in improving the birth weight of neonates was found.
Methodology: A prospective observational study was conducted on 60 preterm neonates. The patients responses before and after initiation of caffeine therapy were recorded. A follow up was conducted after their first discharge and baseline characteristics were recorded to evaluate the improvement.
Results: It was observed that less apneic episodes were seen in pre-terms after initiation of caffeine therapy, the secondary outcomes that retinopathy of prematurity, bronchopulmonary dysplasia, and patent ductus arteriosus were also reduced, with no significant change in birth weight.
Conclusions: Through this study it can be implied that caffeine reduces the risk of apneic episodes, improves the quality of life of neonates and is found to be effective to improve risk of death in preterm.
"EFFICACY OF CAFFEINE ADMINISTRATION IN PRETERM VERY LOW BIRTH WEIGHT (VLBW) INFANTS OF SOUTH INDIA, A PROSPECTIVE OBSERVATIONAL STUDY.", IJNRD - INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT (www.IJNRD.org), ISSN:2456-4184, Vol.9, Issue 10, page no.c566-c576, October-2024, Available :https://ijnrd.org/papers/IJNRD2410269.pdf
Volume 9
Issue 10,
October-2024
Pages : c566-c576
Paper Reg. ID: IJNRD_301305
Published Paper Id: IJNRD2410269
Downloads: 00060
Research Area: Pharmacy All
Country: HYDERABAD, TELANGANA, India
DOI: http://doi.one/10.1729/Journal.42054
ISSN: 2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar | ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
Publisher: IJNRD (IJ Publication) Janvi Wave
