A review on pharmacological activities of Hyoscyamus niger (L.), Curcumin , Mucuna pruriens (L.), & Camellia sinensis (L.).

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Published ID: IJNRD2501118

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Vidya Chandrakant katake, Shreyash Jayawant Patil

Desmethoxycurcumin (DMC) , Bisdemethoxycurcumin (BDMC), Epigallocatechin gallate (EGCG), Hyoscyamus niger (L.),Curcumin , Mucuna pruriens (L.), & Camellia sinensis (L.), anti-Parkinson's, Curcuma longa , L-Dopa, Hyoscyamine , Hyoscine , Scopolamine, Substantia nigra.

Abstract: A) Hyoscyamus niger L. are a significant and large genus within the Solanaceae family. These plant are renowned for their rich content of tropane alkaloids, primarily hyoscyamine and scopolamine, which are of great pharmacological interest. The phytochemical profile of Hyoscyamus species reveals a variety of compounds, including alkaloids, flavonoids, tannins, terpenes, saponins, carbohydrates, cardiac glycosides, and anthraquinones(1,2). Hyoscyamus niger L. commonly known as henbane, belong to family Solanaceae is a plant that has historically played a significant role in traditional medicine, although it is also toxic and must be used with caution(3,6). It belongs to the Solanaceae (nightshade) family and contains several active compounds with medicinal properties, most notably tropane alkaloids like hyoscyamine, scopolamine, and atropine(1,4). B) Curcumin is a natural polyphenolic compound derived from turmeric (Curcuma longa), which is a plant belonging to the Zingiberaceae family. It is the principal active component of turmeric, which gives the spice its characteristic yellow color. Curcumin has been extensively studied for its potential health benefits, particularly its anti-inflammatory, antioxidant, and antimicrobial properties(31). It is thought to exert these effects by modulating various biological pathways, including inhibiting enzymes and transcription factors involved in inflammation, oxidative stress, and cell signaling. As a result, curcumin is often researched for its role in managing conditions like arthritis, cardiovascular disease, and even certain types of cancer(32). C) Mucuna pruriens (L.) common name is (Khaj-kuiri) or (Kavachkuiri) . Mucuna pruriens (L.), commonly known as the velvet bean, is a leguminous plant belonging to the family Fabaceae. It is widely known for its many uses in traditional medicine, agriculture, and as a food source(44). Scientific classification- • Kingdom: Plantae • Clade: Tracheophytes • Order: Fabales • Family: Fabaceae • Subfamily: Faboideae • Genus: Mucuna • Species: M. pruriens(45) Botanical Characteristics • Scientific name: Mucuna pruriens (L.) • Common names: Velvet bean, cowitch, Kapikacchu, Nescafe, and more. • Plant type: Climbing vine or herbaceous plant. • Leaf structure: The leaves are trifoliate (having three leaflets) with large, ovate to lanceolate-shaped leaflets. • Flowers: The plant produces purple to white flowers in clusters. • Fruit/Seed pods: The seeds of Mucuna pruriens are contained in long, hairy pods, which can be quite itchy upon contact with the skin due to the fine hairs. • Seeds: The seeds are kidney-shaped and typically dark brown or black in color. They contain bioactive compounds(44,46). D) Camellia sinensis (L.) Camellia sinensis (L.): commonly known as the tea plant, is a species of evergreen shrub in the Theaceae family, native to East Asia. It is the source of all varieties of tea, including green, black, white, and oolong, depending on how the leaves are processed after harvesting(55). Botanical Characteristics • Scientific name: Camellia sinensis (L.) • Common names: Tea plant, tea bush, green tea (when processed), black tea (when processed), etc. • Plant type: Evergreen shrub or small tree. • Height: Typically grows to a height of 1.5 to 2 meters in cultivation, but it can grow taller in the wild (up to 10 meters). • Leaves: The leaves are dark green, glossy, and leathery with serrated edges. They are alternately arranged and oblong in shape. • Flowers: The flowers are white or pale pink with five petals and a yellow center. They are fragrant but not as showy as many other flowering plants. • Fruit: The plant produces small, woody capsules that contain seeds. Varieties and Types • Green tea: Made from unoxidized leaves, preserving the natural green color and high levels of antioxidants. • Black tea: Made from fully oxidized leaves, giving it a darker color and stronger flavor. • Oolong tea: A partially fermented tea, somewhere between green and black tea in terms of oxidation and flavor. • White tea: Made from the youngest leaves and buds, which are minimally processed and dried, offering a delicate flavor.

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Vidya Chandrakant katake & Shreyash Jayawant Patil (January-2025). A review on pharmacological activities of Hyoscyamus niger (L.), Curcumin , Mucuna pruriens (L.), & Camellia sinensis (L.).. INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT, 10(1), b177-b188. https://ijnrd.org/papers/IJNRD2501118.pdf

Volume 10 Issue 1, January-2025

Pages : b177-b188

Paper Reg. ID: IJNRD_303321

Published Paper Id: IJNRD2501118

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Country: pune, MH, India

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