Paper Title
The Multifaceted Antimicrobial Properties of Terminalia arjuna: A Comprehensive Review and Future Opportunities
Article Identifiers
: Keywords
Antimicrobial, Terminalia arjuna, Bark, Disinfectant, Zone of Inhibition
Abstract
The rise of antimicrobial resistance (AMR) poses a critical threat to global public health, rendering conventional antibiotics increasingly ineffective. This necessitates the exploration of alternative therapeutics, particularly from plant sources. While plant-derived antimicrobials offer promise, challenges remain in standardizing extraction protocols, addressing seasonal variations in phytochemical composition, and establishing safety margins through in vivo studies. Terminalia arjuna (T. arjuna), a cornerstone of Ayurvedic medicine for over 3,000 years, presents a potential solution due to its rich composition of bioactive compounds, including triterpenoids, flavonoids, tannins, and polyphenols. In vitro studies have demonstrated the significant antimicrobial efficacy of T. arjuna extracts against a broad spectrum of Gram-positive and Gram-negative bacteria and fungi, evidenced by pronounced zones of inhibition. This efficacy is attributed to the synergistic action of its multifaceted phytochemicals, which disrupt microbial membranes, inhibit virulence factors, and interfere with essential metabolic pathways. Future research should prioritize the isolation of individual bioactive constituents, elucidate their mechanisms of action at the genetic level, and explore synergistic combinations with existing antimicrobial agents to combat multidrug-resistant pathogens. Furthermore, investigating its potential as a biodegradable disinfection agent warrants exploration.
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How To Cite (APA)
Mayank Arora, Dr. Priyanka Shankar, Dr. Anu Ram Kailash Mishra, & Zia Parveen (May-2025). The Multifaceted Antimicrobial Properties of Terminalia arjuna: A Comprehensive Review and Future Opportunities. INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT, 10(5), a901-a910. https://ijnrd.org/papers/IJNRD2505088.pdf
Issue
Volume 10 Issue 5, May-2025
Pages : a901-a910
Other Publication Details
Paper Reg. ID: IJNRD_306559
Published Paper Id: IJNRD2505088
Downloads: 000121984
Research Area: Life Sciences All
Author Type: Indian Author
Country: lucknow , uttar pradesh , India
Published Paper PDF: https://ijnrd.org/papers/IJNRD2505088.pdf
Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2505088
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