Review: Revolutionizing Drug Delivery And Cancer Therapeutics Through Niosome Innovation

Registration ID: IJNRD_224054

Published ID: IJNRDTH00173

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Miss.Gore Rushali J., Prof.Waghmare S.U, Prof.Akolkar P.B, Miss.Chavan Anushka M., Miss.Hiwarde Dipali B.

Keywords: Cancer, Niosomes, Structure, Drug delivery, Treatment outcomes, Nanocarrier, Formulation techniques; Cancer therapy; Delivery systems.

Niosomes are vesicular nanocarriers, biodegradable, relatively non-toxic, stable, and inexpensive, that provide an alternative for lipid-solid carriers, niosomes similar to liposomes, can tackle challenges associated with instability, rapid degradation, bioavailability, and insolubility of various drugs or natural compounds. Niosomes are highly efficient systems for the targeted delivery of anticancer, antioxidant, anti-inflammatory, antimicrobial, and antibacterial agents. This review aims to provide an overview of their composition, the most common formulation techniques, and recent applications as delivery systems in cancer therapy. Cancer remains a major health concern worldwide, and the need for effective treatment options is crucial. Drug delivery systems, such as niosomes, have shown promise in improving cancer treatment outcomes by enhancing drug delivery efficiency. This review explores the role of niosomes in cancer treatment and how they can improve outcomes through efficient drug delivery. The method, results, Discussion, and conclusion will be discussed in detail Recently, nanotechnology is involved in various feilds of science, of which medicine is one of the most obvious. Nanoparticles have revolutionized the field of disease treatment and diagnosis, offering novel therapeutic strategies with efficient mechanisms of action. Personalized medicine aims to minimize treatment side effects and provide targeted therapies. Therefore, targeted drug delivery is crucial, particularly for patients on combination therapies, as different drug structures often require distinct delivery systems to maintain efficacy. Niosomes, a type of polymeric nanoparticle, have shown promise in drug delivery due to their favorable characteristics. These include biocompatibility, high absorption, reduced drug dosage requirements, and the ability to target drug release. Moreover, Niosome vesicles can encapsulate both hydrophilic and lipophilic drugs, enhancing the versatility and effectiveness of treatment. Various factors, such as components, preparation methods, and optimization techniques, affect the size and formation of niosomal structures. In this review, we first examined the characteristics of niosome vesicles and then explained the in silico tools used for designing, predicting, and optimizing them. We also compared and discussed anticancer drugs delivered by niosomes, highlighting their potential as a model for designing therapeutic strategies. This research aimed to explore all aspects of drug delivery engineering using niosomes, and we presented clinical examples of these nanocarriers in cancer treatment to illustrate their clinical benefits.

Published Paper   E-Certificate

Miss.Gore Rushali J., Prof.Waghmare S.U, Prof.Akolkar P.B, Miss.Chavan Anushka M., & Miss.Hiwarde Dipali B. (June-2024). Review: Revolutionizing Drug Delivery And Cancer Therapeutics Through Niosome Innovation. INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT, 9(6), 162-208. https://ijnrd.org/papers/IJNRDTH00173.pdf

Volume 9 Issue 6, June-2024

Pages : 162-208

Paper Reg. ID: IJNRD_224054

Published Paper Id: IJNRDTH00173

Downloads: 000122046

Research Area: Pharmacy

Author Type: Indian Author

Country: Chh.sambhajinagar, Maharashtra , India

Published Paper PDF: https://ijnrd.org/papers/IJNRDTH00173.pdf

Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRDTH00173

Journal Name: INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT(IJNRD)

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