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INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2456-4184 | Impact factor: 8.76 | ESTD Year: 2016 Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 8.76 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI) |
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| Paper Title: | Development and validation of Q-Absorbance Ratio UV spectrophotometric Method for the simultaneous estimation of metformin and empagliflozin in bulk and pharmaceutical dosage form |
| Authors Name: | Anup Jawale , Mr. Sachin S. Rane , Dr. Rajesh Y. Chaudhari , Dr. Vijay R. Patil , Dr. Lokesh G. Barde |
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IJNRD_180639
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| Published Paper Id: | IJNRD2203034 |
| Published In: | Volume 7 Issue 3, March-2022 |
| DOI: | |
| Abstract: | A simple, robust, precise, UV spectroscopic method has been developed for the simultaneous estimation of Metformin HCL and Empagliflozin in bulk and tablet dosage forms. In this paper the estimation of those drugs was carried out by absorbance ratio method. This method is based on measurement of absorption at 235nm and 258nm i.e., λ max of Metformin and Isoabsorptive point of both Metformin HCL and Empagliflozin respectively. The linearity observed for Metformin HCL is in the range of 10-50μg/ml and for Empagliflozin is in the range of 3-11μg/ml. The accuracy of methods was assessed by recovery studies and was found to be within the range of 99.5%-100.5% for both Metformin HCL and Empagliflozin. The developed methods were validated with respect to linearity, accuracy (recovery), and precision. The method can be employed for estimation of pharmaceutical formulations with no interference from any other excipients and diluents. The results were validated as per ICH guidelines. |
| Keywords: | Empagliflozin, Metformin HCL, Absorption Ratio Method, ICH, Validation etc. |
| Cite Article: | "Development and validation of Q-Absorbance Ratio UV spectrophotometric Method for the simultaneous estimation of metformin and empagliflozin in bulk and pharmaceutical dosage form", International Journal of Novel Research and Development (www.ijnrd.org), ISSN:2456-4184, Vol.7, Issue 3, page no.284-295, March-2022, Available :http://www.ijnrd.org/papers/IJNRD2203034.pdf |
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2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID:IJNRD2203034 Registration ID: 180639 Published In: Volume 7 Issue 3, March-2022 DOI (Digital Object Identifier): Page No: 284-295 Country: Jalgaon, MAHARASTRA, India Research Area: Pharmacy Publisher : IJ Publication Published Paper URL : https://www.ijnrd.org/viewpaperforall?paper=IJNRD2203034 Published Paper PDF: https://www.ijnrd.org/papers/IJNRD2203034 |
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ISSN: 2456-4184
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