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INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2456-4184 | Impact factor: 8.76 | ESTD Year: 2016 Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 8.76 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI) |
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| Paper Title: | Development and Validation of RP-HPLC method for determination of fosinopril sodium and Hydrochlorothiazide in Bulk and in tablet |
| Authors Name: | Miss. Sayali Milind Patil , Mr. Anup R. Jawale , Mr. Sachin S. Rane , Dr. Rajesh Y. Chaudhari , Dr. Vijay R. Patil |
| Download E-Certificate: | Download |
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IJNRD_180646
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| Published Paper Id: | IJNRD2203036 |
| Published In: | Volume 7 Issue 3, March-2022 |
| DOI: | |
| Abstract: | This assay method was Development and Validation of RP-HPLC Method for Determination of Fosinopril Sodium and Hydrochlororthiazide in Bulk and in tablets. They were both drugs separated by using RP-HPLC on a RP- Agilent C18 (250 mm ×4.6 mm I.D.) with particle size 5 µm was selected. On the basis of literature survey the mobile phase was acetonitrile and phosphate buffer was selected at 0.7 ml/min. The UV detector was operated the overlain spectra 233 nm was selected for the estimation of both drugs. Linearity, accuracy, precision, Ruggedness and System suitability test was found to be acceptable concentration ranges 12.5 – 62.5μg/ml for Hydrochlororthiazide and 10-50μg/ml for Fosinopril Sodium with a R20.999 and 0.999 values respectively, in this mixture of drugs. |
| Keywords: | Fosinopril Sodium, Hydrochlororthiazide, Validation, RP-HPLC, Simultaneous Estimation. |
| Cite Article: | "Development and Validation of RP-HPLC method for determination of fosinopril sodium and Hydrochlorothiazide in Bulk and in tablet", International Journal of Novel Research and Development (www.ijnrd.org), ISSN:2456-4184, Vol.7, Issue 3, page no.304-311, March-2022, Available :http://www.ijnrd.org/papers/IJNRD2203036.pdf |
| Downloads: | 000114576 |
| ISSN: |
2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID:IJNRD2203036 Registration ID: 180646 Published In: Volume 7 Issue 3, March-2022 DOI (Digital Object Identifier): Page No: 304-311 Country: Jalgaon, Maharashtra, India Research Area: Pharmacy Publisher : IJ Publication Published Paper URL : https://www.ijnrd.org/viewpaperforall?paper=IJNRD2203036 Published Paper PDF: https://www.ijnrd.org/papers/IJNRD2203036 |
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ISSN: 2456-4184
Impact Factor: 8.76 and ISSN APPROVED
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