|
|||||||||||||||
|
INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2456-4184 | Impact factor: 8.76 | ESTD Year: 2016 Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 8.76 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI) |
||||||||||||||
Issue: April 2024
Volume 9 | Issue 4
Review Result and Publication of Paper within : 2-3 days
Click Here For more DetailsFor Authors
Forms / Download
Published Issue Details
Editorial Board
Other IMP Links
Facts & Figure
Impact Factor : 8.76
Issue per Year : 12
Volume Published : 9
Issue Published : 95
Article Submitted :
Article Published :
Total Authors :
Total Reviewer :
Total Countries :
Indexing Partner
Join RMS/Earn 300
Licence
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License
|
Published Paper Details
|
|
| Paper Title: | “ ANTI-INFLAMMATORY ACTIVITY OF ETHANOLIC EXTRACT OF CASSIA ABSUS AND ITS PHYTOCHEMICAL EVALUATION” |
| Authors Name: | Monika , Dr. Sambath kumar.R , Venkateswaran. V , Dr. Shanmughasundaram. R , Kanagasabai. R |
| Download E-Certificate: | Download |
| Author Reg. ID: |
IJNRD_181237
|
| Published Paper Id: | IJNRD2205048 |
| Published In: | Volume 7 Issue 5, May-2022 |
| DOI: | |
| Abstract: | The aim of present study was to investigate anti-inflammatory activities of its leaves extracts. Anti-inflammatory activities of Ethanolic extracts were evaluated by carageenan induced paw edema. Wister albino rat was used as a model for screening of anti-inflammatory activity. Group I served as disease control and Group II received Indomethacin (10mg/kg/i.p). Group III and IV of experimental animals received low dose (200mg), high dose (400mg) of ethanolic extract of Cassia absus linn. The paw volume was measured for Control, standard and low and high dose of test drug at one hour interval for six hours. From the statistical analysis it was concluded that the ‘Carrageenan induced’ Group I shows the inflammatory action and elevated level of Paw Volume is observed. But the III and IV group deals with the anti-inflammatory activity of the ethanolic extract of leaves of Cassia absus Linn. which gives low Paw Volume at the end of 6th h compared to standard drug. The anti-inflammatory activity is more effective in Group IV Carrageenan induction with oral administration of ethanolic extract of leaves of Cassia absus Linn. of 400 mg/kg/p.o compared to Group III in which Carrageenan given after the oral administration of ethanolic extract of leaves of Cassia absus Linn. of 200 mg/kg/i.p. Significant inhibition of paw edema was observed with both doses tested till the sixth hour. However, maximum inhibition of paw edema was found to be in Group IV 88.01 %. Since carrageenan-induced inflammation model is a significant predictive test for anti-inflammatory agents acting by the mediators of acute inflammation the results of this study are an indication that Cassia absus Linn. can be effective in acute inflammatory disorders.In this study, maximum inhibition of paw edema was found to be in Group IV pretreated with the ethanolic extract of leaves of Cassia absus Linn. (400 mg/kg). |
| Keywords: | Cassia absus , Anti-inflammatory, Carageenan induced paw edema. |
| Cite Article: | "“ ANTI-INFLAMMATORY ACTIVITY OF ETHANOLIC EXTRACT OF CASSIA ABSUS AND ITS PHYTOCHEMICAL EVALUATION”", International Journal of Novel Research and Development (www.ijnrd.org), ISSN:2456-4184, Vol.7, Issue 5, page no.451-460, May-2022, Available :http://www.ijnrd.org/papers/IJNRD2205048.pdf |
| Downloads: | 000118759 |
| ISSN: |
2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
| Publication Details: |
Published Paper ID:IJNRD2205048 Registration ID: 181237 Published In: Volume 7 Issue 5, May-2022 DOI (Digital Object Identifier): Page No: 451-460 Country: Pudukottai, Tamilnadu, India Research Area: Pharmacy Publisher : IJ Publication Published Paper URL : https://www.ijnrd.org/viewpaperforall?paper=IJNRD2205048 Published Paper PDF: https://www.ijnrd.org/papers/IJNRD2205048 |
| Share Article: |
|
|
Click Here to Download This Article |
|
| Article Preview | |
|
|
|
Major Indexing from www.ijnrd.org
| Semantic Scholar | Microsaoft Academic | ORCID | Zenodo |
| Google Scholar | ResearcherID Thomson Reuters | Mendeley : reference manager | Academia.edu |
| arXiv.org : cornell university library | Research Gate | CiteSeerX | PUBLON |
| DRJI | SSRN | Scribd | DocStoc |
ISSN Details
 |
 |
|
ISSN: 2456-4184
Impact Factor: 8.76 and ISSN APPROVED
Journal Starting Year (ESTD) : 2016
DOI (A digital object identifier)
Conference
Open Access License Policy
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License
Important Details
Social Media
Licence
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License
Join RMS/Earn 300
| Copyright © 2024 - All Rights Reserved - IJNRD |
Facebook Twitter Instagram LinkedIn