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INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2456-4184 | Impact factor: 8.76 | ESTD Year: 2016 Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 8.76 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI) |
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| Paper Title: | DEVELOPMENT AND FORMULATION OF POLYHERBAL OINTMENT AND EVALUATION OF ANTIOXIDANTS AND ANTIMICROBIAL POTENTIALS |
| Authors Name: | Ms. Rajnandani Waskel , Mr. Kehar Singh Dhaker , Mrs. Sweety Tiwari , Dr. Akhlesh Kumar Singhai |
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IJNRD_181881
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| Published Paper Id: | IJNRD2206099 |
| Published In: | Volume 7 Issue 6, June-2022 |
| DOI: | |
| Abstract: | The objective of the present investigation was to formulate polyherbal ointment formulation for antioxidant and antibacterial action. Three plants Delonix regia leaves, Annona squamosa leaves and Curcuma longa rhizomes were used in the study and the methanolic extracts of the plant parts were used as the active ingredient of the ointments.The findings suggest the presence of alkaloids, glycosides, phenolics, terpenoids, proteins and flavonoids in the extracts. The total phenolic content in the extracts was determined using Folin-Ciocalteu method and was found to be 27.12, 31.57 and 22.36 GAE mg/g respectively.The polyherbal ointment formulations were prepared using simple ointment base and varying concentration of the DRE, ASE and CLE. The pH of all the formulations was almost equal to the pH of skin and ranged between 5.2 to 5.5. The spreadability value of the formulations revealed good spreading capacity.The antioxidant activity was determined using hydroxy radical scavenging assay method and reducing power assay method. It was found that formulation F2 was having highest antioxidant capacity of the three formulations in both the methods.The in vitro antibacterial action was determined using Staphylococcus aureus as the common bacterial strain utilizing disc diffusion method and the formulation F2 exhibited the highest zone of inhibition. |
| Keywords: | DEVELOPMENT AND FORMULATION OF POLYHERBAL OINTMENT AND EVALUATION OF ANTIOXIDANTS AND ANTIMICROBIAL POTENTIALS |
| Cite Article: | " DEVELOPMENT AND FORMULATION OF POLYHERBAL OINTMENT AND EVALUATION OF ANTIOXIDANTS AND ANTIMICROBIAL POTENTIALS", International Journal of Novel Research and Development (www.ijnrd.org), ISSN:2456-4184, Vol.7, Issue 6, page no.851-864, June-2022, Available :http://www.ijnrd.org/papers/IJNRD2206099.pdf |
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2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID:IJNRD2206099 Registration ID: 181881 Published In: Volume 7 Issue 6, June-2022 DOI (Digital Object Identifier): Page No: 851-864 Country: -, -, - Research Area: Engineering Publisher : IJ Publication Published Paper URL : https://www.ijnrd.org/viewpaperforall?paper=IJNRD2206099 Published Paper PDF: https://www.ijnrd.org/papers/IJNRD2206099 |
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ISSN: 2456-4184
Impact Factor: 8.76 and ISSN APPROVED
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