IJNRD Research Journal

WhatsApp
Click Here

WhatsApp editor@ijnrd.org
IJNRD
INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT
International Peer Reviewed & Refereed Journals, Open Access Journal
ISSN Approved Journal No: 2456-4184 | Impact factor: 8.76 | ESTD Year: 2016
Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 8.76 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI)

Call For Paper

For Authors

Forms / Download

Published Issue Details

Editorial Board

Other IMP Links

Facts & Figure

Impact Factor : 8.76

Issue per Year : 12

Volume Published : 7

Issue Published : 79

Article Submitted : 4920

Article Published : 2292

Total Authors : 5584

Total Reviewer : 667

Total Countries : 75

Indexing Partner

Join RMS/Earn 300

Licence

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License
Published Paper Details
Paper Title: FORMULATION AND EVALUATION OF OCULAR INSERTS OF DICLOFENAC SODIUM FOR CONTROLLED RELEASE DRUG DELIVERY
Authors Name: Devu.Satya Sireesha , B.Lakshmi Prasanna , M.Harini , V.Shirisha , T.Rama Rao
Download E-Certificate: Download
Author Reg. ID:
IJNRD_182794
Published Paper Id: IJNRD2209031
Published In: Volume 7 Issue 9, September-2022
DOI:
Abstract: The main aim of the present study is to formulate an effective ocular inserts of Diclofenac sodium, which can produce a better ocular therapy against ocular infections by increased bioavailability through increased drug-eye contact time and controlling the trans-corneal permeation of drug. We intend to optimize the formulation to show constant release of drug for maintenance of dose over a prolonged period of time. For this purpose we prepared Diclofenac sodium ocular inserts formulations by use of different polymers, HPMC, Eudragit L100, Polyvinyl alcohol at various concentrations and dibutyl phthalate has plasticiser.The prepared formulations were evaluated for various physical and analytical parameter related to appearance, durability, uniformity of drug contents, in-vitro and in-vivo release of drug and for stability. ocular inserts of Diclofenac sodium were prepared by solvent casting method followed by preparing the drug reservoir film and rate controlling membrane separately. Evaluation of ocular inserts for weight and thickness variation were carried out.From current study we can conclude that by using different polymer in rate controlling membrane of an ocusert, release rate of drug from ocusert can be controlled or altered.
Keywords: Ocusert; Clotrimazole; HPMC, Eudragit L100 Polyvinyl alcohol dibutyl phthalate.
Cite Article: "FORMULATION AND EVALUATION OF OCULAR INSERTS OF DICLOFENAC SODIUM FOR CONTROLLED RELEASE DRUG DELIVERY", International Journal of Novel Research and Development (www.ijnrd.org), ISSN:2456-4184, Vol.7, Issue 9, page no.262-272, September-2022, Available :http://www.ijnrd.org/papers/IJNRD2209031.pdf
Downloads: 000110395
ISSN: 2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar| ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
Publication Details: Published Paper ID:IJNRD2209031
Registration ID: 182794
Published In: Volume 7 Issue 9, September-2022
DOI (Digital Object Identifier):
Page No: 262-272
Country: HYDERABAD, telangana, India
Research Area: Pharmacy
Publisher : IJ Publication
Published Paper URL : https://www.ijnrd.org/viewpaperforall?paper=IJNRD2209031
Published Paper PDF: https://www.ijnrd.org/papers/IJNRD2209031
Share Article:
Share

Click Here to Download This Article

Article Preview
Click Here to Download This Article

Major Indexing from www.ijnrd.org
Semantic Scholar Microsaoft Academic ORCID Zenodo
Google Scholar ResearcherID Thomson Reuters Mendeley : reference manager Academia.edu
arXiv.org : cornell university library Research Gate CiteSeerX PUBLON
DRJI SSRN Scribd DocStoc

ISSN Details

ISSN: 2456-4184
Impact Factor: 8.76 and ISSN APPROVED
Journal Starting Year (ESTD) : 2016

DOI (A digital object identifier)


Providing A digital object identifier by DOI
How to Get DOI? DOI

Conference

Open Access License Policy

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License

Creative Commons License This material is Open Knowledge This material is Open Data This material is Open Content

Important Details

Social Media

Licence

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License

Join RMS/Earn 300

IJNRD