INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2456-4184 | Impact factor: 8.76 | ESTD Year: 2016
Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 8.76 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI)
Cubosomes are nanoparticles that primarily consist of specific amphiphilic lipids in a definite proportion and are stabilised by a polymer. They are known as bicontinuous cubic phase liquid crystals. cubosomes have tightly packed, twisted three-dimensional bilayers that resemble "honeycombed" formations and are thermodynamically stable. This honeycombed structure separates a large interfacial area and two internal aqueous channels. The term bicontinuous refers to the breakup of two continuous regions by lipid layer but non intersecting aqueous regions that is wicked into space filling structure. Cubosomes are formed by hydrating a surfactant or polar lipid that produces a cubic phase and then dispersing it into smaller particles. Cubosomes have high drug loading ability because of complex structure. They exhibit rheology like a solid. They have the capacity to encapsulate hydrophobic, hydrophilic, and amphiphilic materials. It enhances the solubility of poorly soluble drugs. These are Bio adhesive and biocompatible. They have various drug loading techniques and high internal surfaces. Other abilities of cubosomes are target and controlled release of bioactive agents. cubosome are versatile systems, administrable by different ways such as orally, percutaneously and parenterally, because of their properties. They are prepared by a simple method. cubosomes have high breaking resistance than liposomes. This article gives an overview on structure, preparation methods, evaluation and applications of cubosomes.
"A review On Cubosomes and their Novel approches", International Journal of Novel Research and Development (www.ijnrd.org), ISSN:2456-4184, Vol.7, Issue 9, page no.1502-1508, September-2022, Available :http://www.ijnrd.org/papers/IJNRD2209177.pdf
Downloads:
000118754
ISSN:
2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar| ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
Facebook Twitter Instagram LinkedIn