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INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2456-4184 | Impact factor: 8.76 | ESTD Year: 2016 Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 8.76 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI) |
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| Paper Title: | Prodrugs : An approach to improve the effectiveness and properties of the drug |
| Authors Name: | Manish S. Junagade , Anju Goyal |
| Download E-Certificate: | Download |
| Author Reg. ID: |
IJNRD_184361
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| Published Paper Id: | IJNRD2211237 |
| Published In: | Volume 7 Issue 11, November-2022 |
| DOI: | |
| Abstract: | A clinically used drug may have limitations in practice because of undesirable side effects, poor solubility, poor bioavailability, short duration of action, first-pass effect, poor absorption & adverse effects. To overcome such undesirable properties, one of the approaches to convert the existing molecule to a more efficient molecule is prodrug design. Prodrug can be synthesized to impart desirable properties in it. Prodrugs are inert in nature but after administration they get activated through metabolic reactions invivo. The activated form then shows the pharmacological activity. Properties of a drug can be improved by selecting proper carrier moiety during its design.The design of mutual prodrug is very fruitful in the area of research & has given successful results in increasing the clinical & therapeutic effectiveness of the drugs.In present article such prodrugs prepared of drugs from various classes are discussed. |
| Keywords: | drugs, undesirable properties. side effects, prodrug design,mutual prodrugs |
| Cite Article: | " Prodrugs : An approach to improve the effectiveness and properties of the drug", International Journal of Novel Research and Development (www.ijnrd.org), ISSN:2456-4184, Vol.7, Issue 11, page no.c273-c287, November-2022, Available :http://www.ijnrd.org/papers/IJNRD2211237.pdf |
| Downloads: | 000118751 |
| ISSN: |
2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID:IJNRD2211237 Registration ID: 184361 Published In: Volume 7 Issue 11, November-2022 DOI (Digital Object Identifier): Page No: c273-c287 Country: Udaipur, Rajasthan, India Research Area: Pharmacy Publisher : IJ Publication Published Paper URL : https://www.ijnrd.org/viewpaperforall?paper=IJNRD2211237 Published Paper PDF: https://www.ijnrd.org/papers/IJNRD2211237 |
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ISSN: 2456-4184
Impact Factor: 8.76 and ISSN APPROVED
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