INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2456-4184 | Impact factor: 8.76 | ESTD Year: 2016
Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 8.76 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI)
Drug delivery technology has become highly competitive and rapidly evolving with ever-increasing demand, but conventional pharmaceutical dosage forms are still dominating. Fast-release dosage forms are those wherein ≥85% of the stated amount of drug dissolves within 30min. The fast-releasing dosage form is one such type of innovative and novel drug delivery system which gaining much attention in the research field. Tablet is the most popular dosage form existing today because of its convenience of self-administration, compactness, and ease to manufacture, sometime immediate onset of action is required than conventional therapy. Fast-release dosage forms disintegrate rapidly after administration with an enhanced rate of dissolution and absorption. The basic approach used in the formulation of tablets is the use of super disintegrants like Polacrilin potassium (Kyron T-314), Cross povidone, Sodium starch glycolate, Croscarmellose sodium, Low-substituted hydroxypropyl cellulose (HPC LS-11), etc. These super disintegrants provide instantaneous disintegration of the tablet after reaches the stomach. The rapid disintegration due to the rapid uptake of water from the medium, swelling, burst effect and thereby promoting bioavailability. The aim of this review article provides different techniques used for preparing fast-release tablets, silent features, various technologies, mechanisms, and the significance of super disintegration in the fast-release of the tablet along with the challenges faced and the limitations.
Keywords:
Fast release Tablet, Polymers, Disintegration, Granulation.
Cite Article:
"FAST RELEASING TABLETS- A NOVEL APPROACH", International Journal of Novel Research and Development (www.ijnrd.org), ISSN:2456-4184, Vol.7, Issue 12, page no.a724-a734, December-2022, Available :http://www.ijnrd.org/papers/IJNRD2212098.pdf
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ISSN:
2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar| ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
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