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IJNRD
INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT
International Peer Reviewed & Refereed Journals, Open Access Journal
ISSN Approved Journal No: 2456-4184 | Impact factor: 8.76 | ESTD Year: 2016
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Impact Factor : 8.76

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Paper Title: Solid Dispersion Methods And Its Advantages: A Review
Authors Name: Anuraag Vyas , Mayuri Thakor , Abhishek Vyavahare , Dipali Yadav , Shubham Yadav
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IJNRD_186936
Published Paper Id: IJNRD2302009
Published In: Volume 8 Issue 2, February-2023
DOI: http://doi.one/10.1729/Journal.32916
Abstract: The solubility behaviour of drug is one of the most challenging aspects in formulation development. Thus, a greater understanding of dissolution and absorption behavior of drug with low aqueous solubility is needed to successfully formulate them into more soluble and hence bioavailable drug product. Solid dispersions have piqued the interest of researchers as an effective technique of increasing the dissolution rate and hence bioavailability of a variety of hydrotrophic medicines. The use of water-soluble carriers in solid dispersions of weakly water-soluble medicines reduces the occurrence of these issues and improves dissolution. "One of the most promising ways for increasing solubility is solid dispersion." ("Solid Dispersion: A Novel Approach to Improving the...") A solid dispersion is a type of solid product that consists of at least two separate components, often a hydrophilic matrix and a hydrophobic medication. The matrix might be crystalline or amorphous in nature. According to the biopharmaceutical categorization system, class II medicines have poor solubility and high permeability and are good candidates for improving bioavailability by solid dispersion. This article discusses the many forms of solid dispersion, various solubility enhancement methodologies in solid dispersion, the benefits of solid dispersion over other techniques, and solid dispersion applications ("(PDF) SOLID DISPERSION - A TECHNIQUE FOR SOLUBILITY ENHANCEMENT OF...").
Keywords: Solubility, Dissolution, Solid Dispersion, Hydrophobic, Hydrophilic, Biopharmaceutical Classification, Enhance Dissolution, Amorphous.
Cite Article: "Solid Dispersion Methods And Its Advantages: A Review", International Journal of Novel Research and Development (www.ijnrd.org), ISSN:2456-4184, Vol.8, Issue 2, page no.a73-a84, February-2023, Available :http://www.ijnrd.org/papers/IJNRD2302009.pdf
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ISSN: 2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar| ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
Publication Details: Published Paper ID:IJNRD2302009
Registration ID: 186936
Published In: Volume 8 Issue 2, February-2023
DOI (Digital Object Identifier): http://doi.one/10.1729/Journal.32916
Page No: a73-a84
Country: Nashik, Maharashtra, India
Research Area: Pharmacy
Publisher : IJ Publication
Published Paper URL : https://www.ijnrd.org/viewpaperforall?paper=IJNRD2302009
Published Paper PDF: https://www.ijnrd.org/papers/IJNRD2302009
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ISSN: 2456-4184
Impact Factor: 8.76 and ISSN APPROVED
Journal Starting Year (ESTD) : 2016

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