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INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2456-4184 | Impact factor: 8.76 | ESTD Year: 2016 Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 8.76 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI) |
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| Paper Title: | Preparation & dose of STZ shows diabetogenic effect |
| Authors Name: | SAZEDUR RAHMAN AKANADA , Sauradeep Das , Imruj Laskar , Dr.Mohibul Hoque |
| Download E-Certificate: | Download |
| Author Reg. ID: |
IJNRD_187709
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| Published Paper Id: | IJNRD2302188 |
| Published In: | Volume 8 Issue 2, February-2023 |
| DOI: | |
| Abstract: | Over the past 30 years, Streptozotocin (STZ) has been widely used to induce diabetes in animals and evaluate hypoglycemic drugs. However, the physicochemical properties and associated toxicity of STZ pose a challenge to researchers. Maintaining uniformity, consistency, reproducibility, and minimal animal mortality in STZ-induced diabetes is also challenging. Proper use of STZ is essential to prevent increased mortality and suffering in animals, and several factors must be considered, such as STZ production method, stability, appropriate dosage, route of administration, diet, animal species, age, body weight, sex, and target blood glucose level. The protocol for STZ-induced diabetes in experimental animals must be carefully developed, and this review provides an overview of diabetogenic mechanisms, specific toxicity, and factors leading to changes in STZ's diabetogenic effects. |
| Keywords: | DM,STZ,DOSE etc. |
| Cite Article: | "Preparation & dose of STZ shows diabetogenic effect", International Journal of Novel Research and Development (www.ijnrd.org), ISSN:2456-4184, Vol.8, Issue 2, page no.b858-b862, February-2023, Available :http://www.ijnrd.org/papers/IJNRD2302188.pdf |
| Downloads: | 000118749 |
| ISSN: |
2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID:IJNRD2302188 Registration ID: 187709 Published In: Volume 8 Issue 2, February-2023 DOI (Digital Object Identifier): Page No: b858-b862 Country: Karimganj, Assam, India Research Area: Pharmacy Publisher : IJ Publication Published Paper URL : https://www.ijnrd.org/viewpaperforall?paper=IJNRD2302188 Published Paper PDF: https://www.ijnrd.org/papers/IJNRD2302188 |
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ISSN: 2456-4184
Impact Factor: 8.76 and ISSN APPROVED
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