Paper Title

BIOCHEMICAL AND LARVICIDAL IMPACT OF APIGENIN AND RUTIN IN THEIR BINARY COMBINATION (1:2) AGAINST ELEPHANTIASIS VECTOR CULEX QUINQUEFASCIATUS

Article Identifiers

Registration ID: IJNRD_203655

Published ID: IJNRD2308149

DOI: Click Here to Get

Authors

Abhay Deep Johnson , Vikas Chandra Verma , Ajay Singh

Keywords

Jatropha gossypifolia, Codiaeum variegatum, Apigenin, Rutin and Culex quinquefasciatus

Abstract

Phytochemicals are safe for non-target organisms like man and vector borne diseases due to insecticidal nature. Larvicidal activity of biologically active compounds i.e. Apigenin and Rutin extracted from the leaves of Jatropha gossypifolia and Codiaeum variegatum against larvae of Culex quinquefasciatus was studied in their binary combination (1:2). Standard WHO protocols was adopted for the larvicidal bioassay. The active compounds i.e. Apigenin and Rutin extracted through ethyl alcohol from the leaves of Euphorbious plants was administered for 24h, 48h, 72h and 96h to the larvae of C. quinquefasciatus. Exposure of larvae over 24h to 96h sub-lethal doses (40% and 80% of LC50) of Apigenin and Rutin in the ratio 1:2, significantly (P<0.05) altered the biochemical levels like total protein, total free amino acid, glycogen and activities of enzymes acetylcholinesterase, acid and alkaline phosphatases in whole body tissue of the larvae. The alteration in all these biochemical parameters were significantly(P<0.05) time and dose dependent. It may act as an ecofriendly measure to manage the population of filarial vector Culex quinquefasciatus.

How To Cite (APA)

Abhay Deep Johnson, Vikas Chandra Verma, & Ajay Singh (August-2023). BIOCHEMICAL AND LARVICIDAL IMPACT OF APIGENIN AND RUTIN IN THEIR BINARY COMBINATION (1:2) AGAINST ELEPHANTIASIS VECTOR CULEX QUINQUEFASCIATUS. INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT, 8(8), b391-b402. https://ijnrd.org/papers/IJNRD2308149.pdf

Issue

Volume 8 Issue 8, August-2023

Pages : b391-b402

Other Publication Details

Paper Reg. ID: IJNRD_203655

Published Paper Id: IJNRD2308149

Downloads: 000121975

Research Area: Engineering

Country: -, -, India

Published Paper PDF: https://ijnrd.org/papers/IJNRD2308149.pdf

Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2308149

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Journal Name: INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT(IJNRD)

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Call For Paper - Volume 10 | Issue 9 | September 2025

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Current Issue: Volume 10 | Issue 9 | September 2025

Impact Factor: 8.76

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