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INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2456-4184 | Impact factor: 8.76 | ESTD Year: 2016 Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 8.76 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI) |
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| Paper Title: | Exosomes - The Innovative biomarkers in diagnosis and management of Alzheimer's disease |
| Authors Name: | G. Supriya Reddy , Adusumilli Mutya Aparna , Komal Singh Shekhawat , Mirdoddi Balaji , T. Rama Rao |
| Download E-Certificate: | Download |
| Author Reg. ID: |
IJNRD_206665
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| Published Paper Id: | IJNRD2310159 |
| Published In: | Volume 8 Issue 10, October-2023 |
| DOI: | |
| Abstract: | Most eukaryotic cells produce exosomes (EXOs), which are tiny extravascular vesicles (30–150 nm in diameter) in the endosomal compartment. They are present in all eukaryotic fluids and are surrounded by phospholipid bilayers, which facilitate a number of crucial cellular processes. Early-stage identification of Alzheimer's disease (AD) is difficult since there are few reliable biomarkers and limited patient access to diagnostic procedures like imaging and cerebrospinal fluid (CSF) studies. According to recent studies, we can say that exosomes could be innovative diagnostic agents for AD because they contain specific chemicals that may be employed as prospective biomarker candidates for early disease detection and prediction before the development of symptoms. Particularly exosomal proteins and microRNAs (miRNAs), which make up the molecular components of exosomes, show considerable promise as new biomarkers for clinical diagnosis and treatment. Due to their presence in the majority of biological fluids, such as blood, urine, saliva, synovial fluid, amniotic fluid, vaginal fluid, breast milk, semen, etc., their extremely high disease-specific bio-molecular signature or profile, the ability of exosomes to carry and exchange various cargos between cells, and their capacity to cross the blood-brain barrier, there has been an increased interest in using exosomes for the diagnosis of neurodegenerative disorders in recent years. In this review, we will discuss the role of exosomes in the treatment and diagnosis of Alzheimer's disease. |
| Keywords: | Alzhiemer’s disease, Exosomes, Neurodegenerative disease, cargo, miRNAs, treatment, diagnosis |
| Cite Article: | "Exosomes - The Innovative biomarkers in diagnosis and management of Alzheimer's disease", International Journal of Novel Research and Development (www.ijnrd.org), ISSN:2456-4184, Vol.8, Issue 10, page no.b534-b551, October-2023, Available :http://www.ijnrd.org/papers/IJNRD2310159.pdf |
| Downloads: | 000118754 |
| ISSN: |
2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID:IJNRD2310159 Registration ID: 206665 Published In: Volume 8 Issue 10, October-2023 DOI (Digital Object Identifier): Page No: b534-b551 Country: Hyderabad, Telangana, India Research Area: Life Sciences Publisher : IJ Publication Published Paper URL : https://www.ijnrd.org/viewpaperforall?paper=IJNRD2310159 Published Paper PDF: https://www.ijnrd.org/papers/IJNRD2310159 |
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ISSN: 2456-4184
Impact Factor: 8.76 and ISSN APPROVED
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