INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2456-4184 | Impact factor: 8.76 | ESTD Year: 2016
Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 8.76 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI)
Two new simple and accurate solvent mediums have been presented for the quantification of Escitalopram Oxalate (ESC) in tablet dosage form. A linear relationship found in the concentration range of 1-24 µg/ml for two proposed mediums viz., Methanol: DW (1:3) solution and Methanol: 0.1N HCl (1:2) solution. The goodness of fit study suggest good correlation coefficient (R2 - 0.9998 and 0.9998 for proposed methods) shows the validity of Beer’s law with intercept response < 2% calculated by the least square method indicating functional linearity between the concentration of analyte and the absorbance. Based on standard deviation of the response and slope, the LOD values for ESC for the proposed mediums found to be 0.348±0.00238 μg/ml, 0.273±0.0014 μg/ml and LOQ values found to be 1.046±0.002458 μg/ml, 0.823±0.00065 μg/ml with % RSD values less than 2. The proposed methods were successfully applied to the determination of commercially available tablets with a high percentage of recovery, good accuracy and precision.
"Spectroscopic Method For Quantification Of Escitalopram Oxalate In Bulk And Tablet Dosage Form", International Journal of Novel Research and Development (www.ijnrd.org), ISSN:2456-4184, Vol.7, Issue 11, page no.a568-a575, November-2022, Available :http://www.ijnrd.org/papers/IJNRD2211063.pdf
Downloads:
000118746
ISSN:
2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar| ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
Facebook Twitter Instagram LinkedIn