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INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2456-4184 | Impact factor: 8.76 | ESTD Year: 2016 Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 8.76 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI) |
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| Paper Title: | IN-VITRO STUDY THE ANTIMICROBIAL ACTIVITY OF AN ALCOHOLIC EXTRACT OF VITEX NEGUNDO LINN. BY DISC DIFFUSION METHOD |
| Authors Name: | Dr. Vikas Gawali , Ganesh Kardile , Suvarna Kothule , Dr. Yogesh Bafna |
| Download E-Certificate: | Download |
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IJNRD_184297
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| Published Paper Id: | IJNRD2211229 |
| Published In: | Volume 7 Issue 11, November-2022 |
| DOI: | |
| Abstract: | In the past decade, the antimicrobial properties of plant extracts have gotten more attention. The current study employs Mueller-Hilton agar-based assays to evaluate several types of leaves of Vitex negundo Linn. (Nirgundi) for in vitro antibacterial activity against gram-positive (Staphylococcus aureus) and gram-negative (Escherichia coli) bacteria (disk diffusion method).The results suggested that the ethanolic extract of Vitex negundo showed zones of inhibition of 12.19 ± 0.445 mm, 17.23 ± 0.761 mm and 21.03± 0.559 mm against Staphylococcus aureus and 09.21± 0.357, 13.88 ± 0.652 and 18.48 ± 0.340 against E coli at concentrations of 100 g/mL, 200 g/mL and 400 g/mL, respectively. The percentage zone of inhibition of alcoholic extract of Vitex negundo 400 g/mL showed 74.93% and 68.95% against S. aureus and E coli, which is significant (P < 0.01) as compared to the positive control group. The aq. extract of Vitex negundo 400 g/mL inhibited S. aureus and E. coli with a significant (P< 0.01) zone of inhibition of 64.22 percent and 52.13 percent, respectively. The findings revealed that the ethanolic extracts of Vitex negundo Linn. Leaf showed a more prominent antibacterial effect than the aqueous extract against S. aureus and E. coli. Respectively. |
| Keywords: | Antimicrobial activity, Vitex negundo Linn. Disk Diffusion Method, S. aureus, E. coli. |
| Cite Article: | "IN-VITRO STUDY THE ANTIMICROBIAL ACTIVITY OF AN ALCOHOLIC EXTRACT OF VITEX NEGUNDO LINN. BY DISC DIFFUSION METHOD", International Journal of Novel Research and Development (www.ijnrd.org), ISSN:2456-4184, Vol.7, Issue 11, page no.c220-c226, November-2022, Available :http://www.ijnrd.org/papers/IJNRD2211229.pdf |
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2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID:IJNRD2211229 Registration ID: 184297 Published In: Volume 7 Issue 11, November-2022 DOI (Digital Object Identifier): Page No: c220-c226 Country: Ahmednagar, Maharashtra, India Research Area: Pharmacy Publisher : IJ Publication Published Paper URL : https://www.ijnrd.org/viewpaperforall?paper=IJNRD2211229 Published Paper PDF: https://www.ijnrd.org/papers/IJNRD2211229 |
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ISSN: 2456-4184
Impact Factor: 8.76 and ISSN APPROVED
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