Development and Evaluation of Punica Granatum Peel Gel as a Potential Anti-Ulcer Agent

Ankita Walunj , Snehal Wagh , Shritej Varhadi , Abhishek Shinde , Bhakti Ingle

Pomegranate, Tulsi, Mouth ulcer gel, Herbal gel.

The herbal gel was prepared by using different concentrations of extract of pomegranate peel powder and Carbopol 934, Propylene paraben as a gel base and other ingredients like Tulsi leaves extract, propyl paraben, propylene glycol, triethanolamine, lemon essential oil, etc. Formulations were evaluated for various parameters. The formulated gel was transparent, homogeneous and pH ranged from 5.5 to 6.8. The formulation showed acceptable rheological behavior with applicable spreadability and extrudability properties. Herbal medicine is still the mainstay of about 75-80% of the world's population, mainly in developing countries, for primary health care because of better cultural acceptability, better compatibility with the human body and lesser side effect from the experimental evidence of invitro studies it was observed that extract of pomegranate peel powder contain tannin so it showed significant anti-inflammatory and antioxidant effect. Developed herbal formulation was stable, safe and effective over to synthetic formulations for the treatment of mouth ulcer. There are number of synthetic gels in the market as compare to herbal or natural gel, synthetic gel has harmful effect on skin like skin irritation and dryness of skin.

Published Paper   E-Certificate

"Development and Evaluation of Punica Granatum Peel Gel as a Potential Anti-Ulcer Agent", IJNRD - INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT (www.IJNRD.org), ISSN:2456-4184, Vol.9, Issue 10, page no.b566-b580, October-2024, Available :https://ijnrd.org/papers/IJNRD2410165.pdf

Volume 9 Issue 10, October-2024

Pages : b566-b580

Paper Reg. ID: IJNRD_301310

Published Paper Id: IJNRD2410165

Downloads: 00017

Research Area: Pharmacy All

Country: Pune, maharashtra, India

Published Paper PDF: https://ijnrd.org/papers/IJNRD2410165

Published Paper URL: https://ijnrd.org/viewpaperforall?paper=IJNRD2410165

ISSN: 2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar | ESTD YEAR: 2016

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Publisher: IJNRD (IJ Publication) Janvi Wave

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