BUCCAL DRUG DELIVERY SYSTEM: THE CURRENT APPROACHES

doi:; ?>

IJNRD Research Journal

WhatsApp
Click Here

editor@ijnrd.org

INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT
International Peer Reviewed & Refereed Journals, Open Access Journal
ISSN Approved Journal No: 2456-4184 | Impact factor: 8.76 | ESTD Year: 2016
Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 8.76 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI)

Submit Paper Online

Call For Paper

Issue: May 2023

Volume 8 | Issue 5

Submit Paper Online

Last date: 31-May-2023

Review Result and Publication of Paper within : 2-3 days

Click Here For more Details

For Authors

Submit Paper Online Publication Guidelines Publication Charges Pay Publication Fees Online Track Paper Research Area All Policy

Forms / Download

Published Issue Details

Current Issue Archive Conference Proposal Recent Conference Details

Editorial Board

Editorial Board Join As A Referral/Reviewer Benefits of Referral/Reviewer

Other IMP Links

START A NEW JOURNAL &
JOURNAL SUPPORTING SOFTWARE Publish BOOK, DISSERTATION AND THESIS Best Research Paper Award

Facts & Figure

Impact Factor : 8.76

Issue per Year : 12

Volume Published : 8

Issue Published : 84

Article Submitted : 17586

Article Published : 5245

Total Authors : 13542

Total Reviewer : 835

Total Countries : 129

Indexing Partner

Join RMS/Earn 300

Licence

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License

Published Paper Details

Paper Title:	BUCCAL DRUG DELIVERY SYSTEM: THE CURRENT APPROACHES
Authors Name:	Mr.Sanjay Shahurao Popale , Dr. Pankaj Motilal Chaudhari , Mrs Smita Pandharinath Wasnik
Download E-Certificate:	Download
Author Reg. ID:	IJNRD_188358
Published Paper Id:	IJNRD2303069
Published In:	Volume 8 Issue 3, March-2023
DOI:
Abstract:	Since the early 1980s there has been renewed interest in the use of bioadhesive polymers to prolong contact time in the various mucosal routes of drug administration. As we all know that, the buccal cavity is highly acceptable by patients, the mucosa is relatively permeable with a rich blood supply. Bypass of the gastrointestinal tract and hepatic portal system, increasing the bioavailability of orally administered drugs that otherwise undergo hepatic firstmetabolism. The buccal region of the oral cavity is an attractive target for administration of the drug of choice, particularly in overcoming deficiencies associated with the latter mode of administration. Problems such as high first-pass metabolism and drug degradation in the gastrointestinal environment can be circumvented by administering the drug via the buccal route. Moreover, rapid onset of action can be achieved relative to the oral route and the formulation can be removed if therapy is required to be discontinued. It is also possible to administer drugs to patients who unconscious and less co- operative. To prevent accidental swallowing of drugs adhesive mucosaldosage forms were suggested for oral delivery, which included adhesive tablets, adhesive gels, adhesive patches and many other dosage forms with various combinations of polymers, absorption enhancers. Natural polymers have recently gained importance in pharmaceutical field. Mucoadhesive polymers are used to improve drug delivery by enhancing the dosage form‟s contact time and residence time with the mucous membranes. Mucoadhesion may be defined as the process where polymers attach to biological substrate or a synthetic or natural macromolecule, to mucus or an epithelial surface. When the biological substrate is attached to a mucosal layer then this phenomenon is known as mucoadhesion. The substrate possessing bioadhesive polymer can help in drug delivery for a prolonged period of time at a specific delivery site. The studies of Mucoadhesive polymers provide a good approach of mucoadhesion and some factors which have the ability to affect the mucoadhesive properties of a polymer. Both natural and synthetic polymers are used for the preparation of mucoadhesive buccal patches. In addition to this, studies have been conducted on the development of controlled or slow release delivery systems for systemic and local therapy of diseases in the oral cavity.. Advantages associated with buccal drug delivery have rendered this route of administration useful for a variety ofdrugs.
Keywords:	Mucoadhesive buccal patch, Natural polymer, Bioadhesive polymers, Buccal formulations, Buccal Mucosa, first-pass effect, permeation enhancers.
Cite Article:	"BUCCAL DRUG DELIVERY SYSTEM: THE CURRENT APPROACHES", International Journal of Novel Research and Development (www.ijnrd.org), ISSN:2456-4184, Vol.8, Issue 3, page no.a672-a683, March-2023, Available :http://www.ijnrd.org/papers/IJNRD2303069.pdf
Downloads:	000113
ISSN:	2456-4184 \| IMPACT FACTOR: 8.76 Calculated By Google Scholar\| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar \| AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
Publication Details:	Published Paper ID:IJNRD2303069 Registration ID: 188358 Published In: Volume 8 Issue 3, March-2023 DOI (Digital Object Identifier): Page No: a672-a683 Country: Ahmednagar , Maharashtra , India Research Area: Pharmacy Publisher : IJ Publication Published Paper URL : https://www.ijnrd.org/viewpaperforall?paper=IJNRD2303069 Published Paper PDF: https://www.ijnrd.org/papers/IJNRD2303069
Share Article:

Click Here to Download This Article

Article Preview

Click Here to Download This Article

Major Indexing from www.ijnrd.org

Semantic Scholar	Microsaoft Academic	ORCID	Zenodo
Google Scholar	ResearcherID Thomson Reuters	Mendeley : reference manager	Academia.edu
arXiv.org : cornell university library	Research Gate	CiteSeerX	PUBLON
DRJI	SSRN	Scribd	DocStoc