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INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT
International Peer Reviewed & Refereed Journals, Open Access Journal
ISSN Approved Journal No: 2456-4184 | Impact factor: 8.76 | ESTD Year: 2016
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Impact Factor : 8.76

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Paper Title: The blood-brain barrier: an overview: mechanisms, functions, treatment & Clinical implications
Authors Name: Asiya Nisa , Swastika Jha , Priyanka
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IJNRD_190220
Published Paper Id: IJNRD2304056
Published In: Volume 8 Issue 4, April-2023
DOI: https://doi.org/10.5281/zenodo.7901862
Abstract: All of the body's tissues and organs depend on blood arteries to carry oxygen and nutrients to them. The blood-brain barrier, a special property of the blood arteries that vascularize the central nervous system (CNS), enables these vessels to tightly control the transit of ions, chemicals, and cells between the blood and the brain. Correct neuronal function is enabled by the careful regulation of CNS homeostasis, which also safeguards neural tissue from toxins and infections. Alterations to these barrier qualities play a significant role in the pathophysiology and development of various neurological illnesses. The endothelial cells (ECs), which make up the blood vessel walls, have a variety of physical, transport, and metabolic characteristics that help to coordinate the physiological barrier. The unique characteristics of the Blood-Brain Barrier must be taken into account in any programme for drug discovery or delivery that seeks to target or avoid the CNS.
Keywords: :- Treatment. Blood–brain barrier; CNS; Degenerative; Disruption; Integrity; Markers; Neuroinflammation; Permeability; TEER; Tight junctions; Transcytosis.
Cite Article: "The blood-brain barrier: an overview: mechanisms, functions, treatment & Clinical implications", International Journal of Novel Research and Development (www.ijnrd.org), ISSN:2456-4184, Vol.8, Issue 4, page no.a462-a472, April-2023, Available :http://www.ijnrd.org/papers/IJNRD2304056.pdf
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ISSN: 2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar| ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
Publication Details: Published Paper ID:IJNRD2304056
Registration ID: 190220
Published In: Volume 8 Issue 4, April-2023
DOI (Digital Object Identifier): https://doi.org/10.5281/zenodo.7901862
Page No: a462-a472
Country: Bangalore, karnataka, India
Research Area: Science
Publisher : IJ Publication
Published Paper URL : https://www.ijnrd.org/viewpaperforall?paper=IJNRD2304056
Published Paper PDF: https://www.ijnrd.org/papers/IJNRD2304056
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ISSN: 2456-4184
Impact Factor: 8.76 and ISSN APPROVED
Journal Starting Year (ESTD) : 2016

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