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IJNRD
INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT
International Peer Reviewed & Refereed Journals, Open Access Journal
ISSN Approved Journal No: 2456-4184 | Impact factor: 8.76 | ESTD Year: 2016
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Paper Title: An Assessment on Emphasis of Chlorpyrifos on Human Health and Environment
Authors Name: MANISHA RANI , DR. SUNIL KUMAR SINGH , DR. ASHOK KUMAR THAKUR
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IJNRD_192446
Published Paper Id: IJNRD2304563
Published In: Volume 8 Issue 4, April-2023
DOI:
Abstract: Among the organophosphate pesticides Chlorpyrifos (CPF) is one of the oldest, wide-spectrum insecticides, used in public health and residential to kill a variety of insects and control the vectors of diseases. Although, the primary toxicity associated with CPF is cholinergic symptoms resulting from acetylcholinesterase inhibition and consequent accumulation of CPF in the body causes toxic effects on the different systems of exposed living beings, such as muscular, nervous, immune, and endocrine alterations. Several studies have reported that CPF has the potential to induce ROS (Reactive Oxygen Species), lipid peroxidation, and enzyme inactivation of cellular membranes through various biochemical processes, and the metabolites produces by the oxidation of CPF show a pattern of induction of chromosome damage and has been related to mutagenicity, carcinogenicity, teratogenicity, and DNA abnormalities. CPF induces toxicity in soil, air as well as water by decreasing their nutrients. In plants, CPF reduces carbon dioxide assimilation ability, and the nitrogen fixation rate also disrupts the chlorophyll biosynthesis pathway. It is also hepatotoxic, genotoxic as well as renal toxic in mammals and shows a large toxic impact on the male reproductive system. This review is based on scientific reports, data, and previous research that had been done in previous years which explain the toxic effect of CPF in a complete environment, in both abiotic and biotic factors, and show the risk to human health due to the use of CPF. KEYWORDS: Chlorpyrifos (CPF); Organophosphate; toxic effect; human health; environment;
Keywords: Chlorpyrifos (CPF); Organophosphate; toxic effect; human health; environment;
Cite Article: "An Assessment on Emphasis of Chlorpyrifos on Human Health and Environment", International Journal of Novel Research and Development (www.ijnrd.org), ISSN:2456-4184, Vol.8, Issue 4, page no.f548-f554, April-2023, Available :http://www.ijnrd.org/papers/IJNRD2304563.pdf
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ISSN: 2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar| ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
Publication Details: Published Paper ID:IJNRD2304563
Registration ID: 192446
Published In: Volume 8 Issue 4, April-2023
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Page No: f548-f554
Country: bhagalpur, bihar, India
Research Area: Life Sciences 
Publisher : IJ Publication
Published Paper URL : https://www.ijnrd.org/viewpaperforall?paper=IJNRD2304563
Published Paper PDF: https://www.ijnrd.org/papers/IJNRD2304563
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ISSN: 2456-4184
Impact Factor: 8.76 and ISSN APPROVED
Journal Starting Year (ESTD) : 2016

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