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INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2456-4184 | Impact factor: 8.76 | ESTD Year: 2016 Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 8.76 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI) |
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| Paper Title: | Review on Potential Activity of synthetic coumarins as Anti-Inflammatory agents |
| Authors Name: | Anita Singh , Sakshi Gupta , Komalpreet Kaur , Amrita Verma Pargaien |
| Download E-Certificate: | Download |
| Author Reg. ID: |
IJNRD_206500
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| Published Paper Id: | IJNRD2304734 |
| Published In: | Volume 8 Issue 4, April-2023 |
| DOI: | |
| Abstract: | Inflammation is a defense mechanism used by body tissues to protect them against stimuli that they perceive to be harmful, such as pathogens, damaged cells, and irritants. The most common treatments for inflammation are nonsteroidal anti-inflammatory drugs (NSAIDs). Coumarin and its derivatives have some basic pharmacological properties like anti-inflammatory, anti-coagulant, antibacterial, antifungal, anti-HIV, antioxidant, antidepressants, antidiabetic, anti-allergic, anti-cancer, anti-proliferative, and antiviral. The purpose of this review is to investigate the synthetic scheme of novel coumarin derivatives that have been reported to have COX-1, COX-2, and TNF-alpha inhibitor activity. Various of the compounds described have also undergone in-vivo testing. Also, we performed in-silico study of various lead compounds originated from mentioned synthetic strategies against 4PH9 and 2AZ5 receptor. |
| Keywords: | Coumarins, Inflammation, NSAIDs, Cyclooxygenase, TNF-Alpha |
| Cite Article: | "Review on Potential Activity of synthetic coumarins as Anti-Inflammatory agents", International Journal of Novel Research and Development (www.ijnrd.org), ISSN:2456-4184, Vol.8, Issue 4, page no.h263-h274, April-2023, Available :http://www.ijnrd.org/papers/IJNRD2304734.pdf |
| Downloads: | 000118766 |
| ISSN: |
2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID:IJNRD2304734 Registration ID: 206500 Published In: Volume 8 Issue 4, April-2023 DOI (Digital Object Identifier): Page No: h263-h274 Country: Bhimtal, Uttarakhand, India Research Area: Pharmacy Publisher : IJ Publication Published Paper URL : https://www.ijnrd.org/viewpaperforall?paper=IJNRD2304734 Published Paper PDF: https://www.ijnrd.org/papers/IJNRD2304734 |
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ISSN: 2456-4184
Impact Factor: 8.76 and ISSN APPROVED
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