INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2456-4184 | Impact factor: 8.76 | ESTD Year: 2016
Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 8.76 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI)
Irrational antibiotic therapy cause bacterial resistance, increase side effects of drugs, increase morbidity, increase total hospital costs. The Access, Watch, Reserve (AWaRe) classification of antibiotics formulated by World Health Organisation with the goals of better accessibility and clinical outcomes, a decreased probability of antimicrobial resistance, safeguarding the effectiveness of last-resort antibiotics and to evaluate the rational use of antibiotics. In this study a retrospective observational analysis was conducted over a period of six months in a tertiary care hospital. The objectives of the study was to evaluate the dosage adjustments of antibiotics in chronic kidney disease using Cockcroft – Gault formula and to examine prescription pattern of antibiotics using AWaRe classification of WHO. A total of 100 patient case records satisfying the inclusion criteria were analysed. High consumption of watch-group antibiotics was observed in the study. Ceftriaxone+ sulbactam was the most commonly prescribed antibiotic followed by cefixime. There were 13 irrational antibiotics prescribed in the study population, which are Inj. Piperacillin + Tazobactam , Tab. Cefixime, Inj. Imipenem, Inj. Ceftriaxone etc. Incidence of irrational dosage promotes the need for individualized dosage regimen to patients with Chronic Kidney Disease. Understanding and implementation of dosage adjustment is important to avoid drug toxicity.
Keywords:
Chronic Kidney Disease, AWaRe classification, Dosage adjustment, Antibiotics, World Health Organisation
Cite Article:
"EVALUATION OF ANTIBIOTIC PRESCRIPTION PATTERN USING WHO AWaRe CLASSIFICATION AND ANTIBIOTICS DOSAGE ADJUSTMENT IN PATIENTS WITH CHRONIC KIDNEY DISEASE", International Journal of Novel Research and Development (www.ijnrd.org), ISSN:2456-4184, Vol.8, Issue 5, page no.b397-b405, May-2023, Available :http://www.ijnrd.org/papers/IJNRD2305151.pdf
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ISSN:
2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar| ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
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