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INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2456-4184 | Impact factor: 8.76 | ESTD Year: 2016 Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 8.76 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI) |
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| Paper Title: | A review on gastro-retentive mucoadhesive microspheres |
| Authors Name: | Rajesh h j , Dr. Parthiban S |
| Download E-Certificate: | Download |
| Author Reg. ID: |
IJNRD_193864
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| Published Paper Id: | IJNRD2305189 |
| Published In: | Volume 8 Issue 5, May-2023 |
| DOI: | |
| Abstract: | Drugs that are easily absorbed from the gastrointestinal tract (GIT) and have a short half-life are eliminated quickly from the blood circulation and require frequent dosing. To avoid this, and increase the gastric residence time developed GRDDS. The gastroretentive drug delivery system is a novel drug delivery system to prolong gastric retention time thereby targeting the drug to the desired site i.e. to the upper gastrointestinal tract for local or systemic action improving the bioavailability of the drugs. Mucoadhesion is the process whereby synthetic and natural polymers adhere to mucosal surfaces in the body. If these materials are then incorporated into pharmaceutical formulations, drug absorption by mucosal cells may be enhanced or the drug will be released at the site for an extended period. mucoadhesive drug delivery systems generally are the family of hydrogels, such as natural gums, polyacrylates, and cellulose ethers. Microspheres, in general, have the potential to be used for targeted and controlled-release drug delivery. Mucoadhesive microspheres are an ideal targeting system with high safety profile and have been developed for oral, buccal, nasal, ocular, rectal, and vaginal for either systemic or local effects. |
| Keywords: | gastroretentive drug delivery, physiology of stomach, mucoadhesive microsphere preparation, evaluation, current research outcome. |
| Cite Article: | "A review on gastro-retentive mucoadhesive microspheres", International Journal of Novel Research and Development (www.ijnrd.org), ISSN:2456-4184, Vol.8, Issue 5, page no.b680-b690, May-2023, Available :http://www.ijnrd.org/papers/IJNRD2305189.pdf |
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| ISSN: |
2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID:IJNRD2305189 Registration ID: 193864 Published In: Volume 8 Issue 5, May-2023 DOI (Digital Object Identifier): Page No: b680-b690 Country: Mandya , Karnataka, India Research Area: Pharmacy Publisher : IJ Publication Published Paper URL : https://www.ijnrd.org/viewpaperforall?paper=IJNRD2305189 Published Paper PDF: https://www.ijnrd.org/papers/IJNRD2305189 |
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ISSN: 2456-4184
Impact Factor: 8.76 and ISSN APPROVED
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