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INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2456-4184 | Impact factor: 8.76 | ESTD Year: 2016 Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 8.76 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI) |
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| Paper Title: | CURRENT TRENDS IN POLYMER MICRONEEDLE FOR TRANSDERMAL DRUG DELIVERY |
| Authors Name: | Lomate pragati pramod , Halse Aditya B , Patil Laxmi R , Dr. Bavge Shyamila B. , Joshi Deepak A. |
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IJNRD_185031
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| Published Paper Id: | IJNRD2305410 |
| Published In: | Volume 8 Issue 5, May-2023 |
| DOI: | |
| Abstract: | TDD is a painless method of delivering drugs systemically by applying a medication formulation onto intact and healthy skin .The drug firstly penetrates through the stratum corneum and then passes through the epidermis and dermis without drug accumulation in the dermal layer. Transdermal drug delivery utilizing microneedles is increasingly gaining interest because to the issues related with oral drug delivery routes. Gastrointestinal route open the drug to acid and enzymes present in the stomach, leading to denaturation of the compound and resulting in poor bioavailability.Microneedle transdermal drug delivery resolves the problems linked to oral delivery and to relieves the discomfort of patients associated with injections to increase patient compliance.Microneedles can be classified into five types: solid microneedles, coated microneedles, dissolving microneedles, hollow microneedles, and hydrogel-forming microneedles. The materials used for the preparation of microneedles ditect the various applications and features present in the microneedle. Polymeric microneedle exhibit present an improved method for transdermal administration of drugs as they penetrate the skin stratum corneum barrier with minimal invasiveness. The review summarizes the significance of polymeric microneedle and discussed some of the most important therapeutic drugs in research, mainly protein drugs, vaccines and small molecule drugs in regenerative medication. |
| Keywords: | Skin,Transdermal route, Microneedles, Drug delivery system, Polymer microneedles. |
| Cite Article: | "CURRENT TRENDS IN POLYMER MICRONEEDLE FOR TRANSDERMAL DRUG DELIVERY", International Journal of Novel Research and Development (www.ijnrd.org), ISSN:2456-4184, Vol.8, Issue 5, page no.e98-e108, May-2023, Available :http://www.ijnrd.org/papers/IJNRD2305410.pdf |
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2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID:IJNRD2305410 Registration ID: 185031 Published In: Volume 8 Issue 5, May-2023 DOI (Digital Object Identifier): Page No: e98-e108 Country: Latur, Maharashtra , India Research Area: Pharmacy Publisher : IJ Publication Published Paper URL : https://www.ijnrd.org/viewpaperforall?paper=IJNRD2305410 Published Paper PDF: https://www.ijnrd.org/papers/IJNRD2305410 |
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ISSN: 2456-4184
Impact Factor: 8.76 and ISSN APPROVED
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