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INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2456-4184 | Impact factor: 8.76 | ESTD Year: 2016 Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 8.76 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI) |
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| Paper Title: | AN EVALUATION OF ANTI-INFLAMMATORY ACTION OF PADMAK AGAD IN WISTAR ALBINO RAT- A RESEARCH ARTICLE |
| Authors Name: | Dr. Varsha Bansal , Dr. Ramesh Chandra Tiwari , Dr. Bhawana Mittal , Mr. Gaurav Sharma |
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IJNRD_200008
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| Published Paper Id: | IJNRD2306433 |
| Published In: | Volume 8 Issue 6, June-2023 |
| DOI: | |
| Abstract: | Background- Padmak Agad is a vishahara yoga. The prabhava of the yoga is said to “Ashesh keetlootanam agad sarvakamik” (A.H.U 37 / 28)1 i.e. it is effective in all types of keet and loota visha to relieve all the symptoms of insect bite. Insect bite can cause an immediate skin reaction, often resulting in redness and swelling at the injured site. Regardless of the triggering aetiology, inflammation is the initial response of the host defence mechanism to infection, irritants, or foreign bodies. When it becomes severe, it leads to tissue damage. It is a complex interplay of enzyme activation, mediator release, fluid extravasation, cell migration, tissue breakdown and repair that can sometimes produce systemic signs and symptoms such as fever, malaise, loss of appetite, and so on. Therefore, control of inflammation is critical phenomenon. Material and methods-Paw edema model was selected for the present study. Eighteen Wistar albino rats had been divided in to three groups each group contain six mice. First group was negative control group; second group was test drug group while third group was standard group. Test drug was given to the group 2 for 1 days O.D. Result- When we performed the paw edema model, thickness of paw was 6.57±0.538, 5.95±0.518, 5.67±0.273, 5.02±0.250 at the end of 0, 3, 6 and 24 hrs respectively. While the volume of paw was 0.94±0.048, 0.83±0.037, 0.77±0.022, 0.79±0.027 at the end of 0, 3, 6 and 24 hrs respectively. On applying Dunnett's multiple comparisons test to compare the group 1 to group 2 and group 1 to group 3, there was statistically significant role of test drug in Paw edema model. Discussion and Conclusion- Significant anti-inflammatory effect of Padmak Agad is found in tail clip model. |
| Keywords: | Insect bite, Paw edema, inflammation, Keet visha, Padmak Agad |
| Cite Article: | "AN EVALUATION OF ANTI-INFLAMMATORY ACTION OF PADMAK AGAD IN WISTAR ALBINO RAT- A RESEARCH ARTICLE", International Journal of Novel Research and Development (www.ijnrd.org), ISSN:2456-4184, Vol.8, Issue 6, page no.e242-e249, June-2023, Available :http://www.ijnrd.org/papers/IJNRD2306433.pdf |
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2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID:IJNRD2306433 Registration ID: 200008 Published In: Volume 8 Issue 6, June-2023 DOI (Digital Object Identifier): Page No: e242-e249 Country: Haridwar, Uttarakhand, India Research Area: Medical Science Publisher : IJ Publication Published Paper URL : https://www.ijnrd.org/viewpaperforall?paper=IJNRD2306433 Published Paper PDF: https://www.ijnrd.org/papers/IJNRD2306433 |
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