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INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2456-4184 | Impact factor: 8.76 | ESTD Year: 2016 Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 8.76 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI) |
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| Paper Title: | FORMULATION AND EVALUATION OF NIOSOMES CONTAINING CEFETAMET PIVOXIL |
| Authors Name: | Manjeet Sharma , Kaushalya Bains |
| Download E-Certificate: | Download |
| Author Reg. ID: |
IJNRD_201495
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| Published Paper Id: | IJNRD2307248 |
| Published In: | Volume 8 Issue 7, July-2023 |
| DOI: | |
| Abstract: | Cefetamet pivoxil is an oral, broad spectrum third generation antibiotic belonging to class of Cephalosporins. Cefetamet pivoxil has shown its anti-biotic activity against both Gram positive and Gram negative bacteria and has high stability in the presence of β-lactamase except Enterococci species. This study was aimed at developing and optimizing niosomal formulation of Cefetamet pivoxil in order to improve its bioavailability. in this study, the niosomes of Cefetamet pivoxil will be prepared by using non-ionic surfactant in varied concentration (Span 60) and cholesterol employing thin-film hydration technique. The prepared formulation will be characterized for several parameters such as physical appearance, pH, Scanning Electron Microscopy, Drug content, Drug entrapment efficiency, in vitro microbiological study, in vitro drug release, and stability studies. From the result of all characterization parameters the in vitro drug release from formulation F4 was found to be optimum. From the release kinetics of formulation F4 it was found that the First order release kinetics was best fitted for niosomes. |
| Keywords: | Niosomes, Cefetamet pivoxil, Cholesterol, Span 60, Dissolution. |
| Cite Article: | " FORMULATION AND EVALUATION OF NIOSOMES CONTAINING CEFETAMET PIVOXIL", International Journal of Novel Research and Development (www.ijnrd.org), ISSN:2456-4184, Vol.8, Issue 7, page no.c434-c439, July-2023, Available :http://www.ijnrd.org/papers/IJNRD2307248.pdf |
| Downloads: | 000118764 |
| ISSN: |
2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID:IJNRD2307248 Registration ID: 201495 Published In: Volume 8 Issue 7, July-2023 DOI (Digital Object Identifier): Page No: c434-c439 Country: Sirmaur, Himachal Pradesh, India Research Area: Pharmacy Publisher : IJ Publication Published Paper URL : https://www.ijnrd.org/viewpaperforall?paper=IJNRD2307248 Published Paper PDF: https://www.ijnrd.org/papers/IJNRD2307248 |
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ISSN: 2456-4184
Impact Factor: 8.76 and ISSN APPROVED
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