INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2456-4184 | Impact factor: 8.76 | ESTD Year: 2016
Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 8.76 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI)
Seizures in term babies and neurodevelopmental outcome: a follow-up study
Prof. M A Wahed, Head of Child Health, Rangpur Mother and Children Hospital, Bangladesh.
Abstract
Introduction: Neonatal period is the most vulnerable time for the occurrence of seizures. There are various etiological factors of neonatal seizures and increasing evidence suggests that neonatal seizures are associated with adverse neurodevelopment outcomes.
Objectives: The objectives were determination of causes of neonatal seizures with outcome during management and long-term post-natal outcome.
Material & Methods: This was a prospective cross-sectional Hospital based study conducted in Rangpur Mother and Children Hospital from 1st July to 2017 to 30th June 2022. Term newborn babies admitted in Neonatal Intensive Care Unit with convulsion were the samples. A prepared and pretested “Protocol” containing Part-A and Part-B was used - Part-A in Neonatal Intensive Care Unit and Part-B in the attached Disability Research Center for periodic follow up. Standard guidelines were followed in clinical diagnosis, laboratory investigations and management of convulsion. The survivors were followed-up periodically. Simple statistical calculations were performed.
Results: A total of 234 term neonates with convulsion were admitted from 1st July 2017 to 30th June 2018. Among them, 15 expired during treatment, 10 babies taken out on Risk Bond by parents and 212 children were discharged and referred to Disability Research Center for follow-up assessment. Follow-up was continued up to 30th June 2022 and 37 children were lost from regular follow-up. Finally, data from 175 children were analyzed. Among these 110 (62.9%) children were male and 65 (27.1%) were female. HIE stage-II was present in 133 (76.0%) samples and 20 (11.3%) had metabolic disturbances. Clonic convulsion was present in 114 (65.0%) samples and subtle convulsion in 45 (26.0%) samples. HIE was the potent predictor for developing neurodevelopmental sequelae.
Conclusions: Neonatal seizures have different etiology. Among them HIE stage-II is the predominant cause of admission as well as adverse neurodevelopmental outcomes.
Keywords:
Key words: Term baby, convulsion, NICU admission, neurodevelopmental outcome.
Cite Article:
"Seizures in term babies and neurodevelopmental outcome: a follow-up study", International Journal of Novel Research and Development (www.ijnrd.org), ISSN:2456-4184, Vol.8, Issue 8, page no.b184-b192, August-2023, Available :http://www.ijnrd.org/papers/IJNRD2308123.pdf
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ISSN:
2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar| ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
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