INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2456-4184 | Impact factor: 8.76 | ESTD Year: 2016
Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 8.76 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI)
Abstract:
The gut microbiota modifies drugs, impacting their effects through chemical changes. Recent research uncovers complex microbe-drug interactions that can alter treatment outcomes. Drugs and the gut microbiome can mutually affect each other, changing drug processing and effects.Therapeutic drugs and xenobiotics can alter the gut microbiome's makeup and functions. These changes can affect how drugs are chemically transformed, influencing treatment outcomes.Colorectal cancer (CRC) is a prevalent and lethal disease, linked to factors like genetics and lifestyle. Current treatments often lead to negative effects, affecting patients' well-being. Probiotics have emerged as a promising approach to alleviate treatment side effects and enhance the health of CRC patients.The review discusses microbial drug modification genetics, drug effects on gut microbes, and the gut microbiota's involvement in drug metabolism and how probiotics can improve CRC patient’s condition by bolstering gut health, releasing protective substances, and enhancing intestinal functions. The effectiveness of probiotics depends on factors such as strain selection, dosage, and individual physiology. Identifying potent probiotic strains is essential for developing targeted CRC therapies
Keywords:
Keywords: Gut microbiome,Xenobiotics, Colorectal cancer, Probiotics, Drug metabolism
Cite Article:
"MICROBIOTA -MEDIATED METABOLISM AND PROBIOTICS INTERVENTIONS IN COLORECTAL CANCER: A REVIEW", International Journal of Novel Research and Development (www.ijnrd.org), ISSN:2456-4184, Vol.8, Issue 8, page no.b431-b434, August-2023, Available :http://www.ijnrd.org/papers/IJNRD2308152.pdf
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ISSN:
2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar| ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
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