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INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2456-4184 | Impact factor: 8.76 | ESTD Year: 2016 Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 8.76 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI) |
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| Paper Title: | Evaluation of CNS Depressant Activity of Different Plant parts of Aegle marmelos Linn |
| Authors Name: | jitendra jaiswal , jitendra jaiswal , DR. Vivekanand katare |
| Download E-Certificate: | Download |
| Author Reg. ID: |
IJNRD_203170
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| Published Paper Id: | IJNRD2308254 |
| Published In: | Volume 8 Issue 8, August-2023 |
| DOI: | |
| Abstract: | The present study was carried out with the water-soluble portion of the ethanol extracts of flowers, barks, seeds and leaves of Linn. Aegle marmelos The ethanol extracts of the plant parts were obtained by soxhlet extraction. After performing the gross behavioral study, the CNS depressant activity was evaluated by observing the prolongation of sleeping time induced by pentobarbital sodium in mice. Attempts have been made to explore the possible mechanism behind this activity by determining their effect on brain monoamine neurotransmitters like dopamine and serotonin. The gross behavioral study showed that ethanol extracts of the leaves, flowers and seeds possess significant CNS depressant activity. The leaves, flowers, seeds and barks (600 mg/kg) showed significant and dose-dependent prolongation of onset and duration of sleep and so found to cause decrease dopamine and increase serotonin level. From which it can be concluded that the CNS depressant activity of the ethanol extracts of seeds, leaves and flowers may be due to the decrease in dopamine and increase in serotonin level. |
| Keywords: | Keywords: Aegle marmelosL., behavioral study, CNS depressant activity, histamine, serotonin |
| Cite Article: | "Evaluation of CNS Depressant Activity of Different Plant parts of Aegle marmelos Linn", International Journal of Novel Research and Development (www.ijnrd.org), ISSN:2456-4184, Vol.8, Issue 8, page no.c391-c399, August-2023, Available :http://www.ijnrd.org/papers/IJNRD2308254.pdf |
| Downloads: | 000118749 |
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2456-4184 | IMPACT FACTOR: 8.76 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.76 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID:IJNRD2308254 Registration ID: 203170 Published In: Volume 8 Issue 8, August-2023 DOI (Digital Object Identifier): Page No: c391-c399 Country: mahuagaon district singrauli, Madhya Pradesh, India Research Area: Pharmacy Publisher : IJ Publication Published Paper URL : https://www.ijnrd.org/viewpaperforall?paper=IJNRD2308254 Published Paper PDF: https://www.ijnrd.org/papers/IJNRD2308254 |
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ISSN: 2456-4184
Impact Factor: 8.76 and ISSN APPROVED
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